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Acetyl
a “tag” that causes DNA to wrap loose around nucleosomes, which “turns off” the gene, causing increased gene expression
Anaphase
The third stage of Mitosis and Meiosis where the spindle fibers pull the chromatids apart
Antiparallel
Parallel but moving in opposite directions, the way a DNA spirals
Backbone
the structural support of the DNA molecule. Made up of alternating deoxyribose and phosphate groups
Centromeres
the joint region of sister chromatids, where spindle fibers can attach during cell division
Chromatid
one the the two “sister” chromatids, where spindle fibers can attach during cell division
Chromatid
“packaged” form of DNA
Chromosome
a single condensed DNA molecule
Cytokinesis
after telophase and PMAT, a cell wall appears at the center, and the cytoplasm fully splits, dividing the cell into 2 daughter cells
Deoxyribose
a pentose (5-carbon) sugar which makes up part of the DNA molecule’s backbone along with phosphate
Diploid
a cell containing 2 complete sets of chromosomes, one from each parent (2n)
DNA
DeoxyriboNucleic Acid, a molecule that carries genetic info for developing a functioning organism
Double Helix
the shape and structure of the DNA strand
Gametes Cells
sex cells, a haploid cell
Haploid
a single set of unpaired chromosomes (n)
Histones
a type of protein found in the chromosome. Gives chromosomes their shape, and helps control the activity with genes as tags.
Hydrogen bonds
a weak bond between 2 molecules, but the large numbers provide crucial stability for the DNA strand
Interphase
a phase where G1, S1, and G2 occurs, before mitosis or meiosis (PMAT)
Major groove
the wider space between the two strands of the DNA double helix
Meiosis
A type of cell division that results in 4 unique daughter cells, and primarily only for gametes
Metaphase
the second stage of cell division, where spindle fibers attach to the centromere of the chromosomes
Methyl
a “tag” that causes DNA to wrap tighter around nucleosomes, which “turns off” the gene, causing decreased gene expression
Minor groove
the narrower space between the two strands of the DNA double helix
Mitosis
a type of cell division that results in 2 identical daughter cells, and primarily only for somatic (not sexual) cells
Nitrogenous base
Adenine pairs with Thymine in DNA, A pairs with Uracil in RNA. Guanine pairs with cytosine. (think: at group chat AT GC)
Nucleosomes
groups of proteins that DNA wraps around
Nucleotide
the organic molecules that make up a nitrogenous base (phosphate and deoxyribose)
P-Arm
the short arm of a chromosome
Phosphate
PO4, a key component in the DNA molecule’s backbone along with phosphate
Prophase
the first stage of cell division where the chromosomes become visible as paired chromatids
Q-Arm
the long arm of a chromosome
Single strand
typically associated with RNA, a single-strand molecule
Sister Chromatids
identical copies of a chromosome that are held together during replication
Somatic cells
body cells, a diploid cell
Telophase
the fourth/final stage of cell division, where 2 new nuclei are formed
5-prime end
5th carbon of deoxyribise sugar ring, what phosphate bonds to
3-prime end
3rd carbon of deoxyribose sugar ring
Dehydration Synthesis
a chemical reaction involving removing an H20 molecule from 2 molecules to create one bigger molecule
Hydrolysis
a chemical reaction where a molecule is broken down by a reaction with an H20 molecule, usually needs an enzyme to help the H20 break molecule apart.
Helicase
an enzyme that breaks the hydrogen bonds in DNA strands
DNA Polymerase
an enzyme that builds the polymer of DNA by adding onto only the 3 prime end
Leading Strand
“good guy strand” adds DNAP smoothly because the DNAP can just follow the helicase
Lagging Strand
“scumbag strand” a strand that reads 3 prime to 5 prime, so the DNAP can only add on in small sections since it can’t follow the helicase
Ligase
an enzyme that “glues” together all the segments of DNA, and checks over the patterns
Primase
an enzyme that lays down RNA primer to get DNAP to start replicating
Polymers
repeating monomers
Base Sequence
AT || GC
AU (RNA only)
RNA
RiboNucleic Acid is a single stranded molecule and has ribose sugar. Has Uracil instead of Thymine