Acetyl | A “tag” that causes DNA to wrap loose around nucleosomes, which “turns off” the gene, causing increased gene expression. | |
Anaphase | The third stage of Mitosis & Meiosis where the spindle fibers pull the chromatids apart. | |
Antiparallel | Parallel but moving in opposite directions, the way a DNA spirals | |
Backbone | The structural support of the DNA molecule. Made up of alternating deoxyribose and phosphate groups. | |
Centromeres | The joint region of sister chromatids, where spindle fibers can attach during cell division. | |
Chromatid | One of the two “sister” chromatids, where identical halves of a chromosome that was replicated. | |
Chromatin | “Packaged” Form of DNA | |
Chromosome | A single condensed DNA molecule | |
Cytokinesis | After Telophase and PMAT over all. A cell wall appears at the center, and the cytoplasm fully splits, dividing the cell into 2 daughter cells. | |
Deoxyribose | A pentose (5-carbon) sugar which makes up part of the DNA molecule’s backbone along with Phosphate | |
Diploid | A cell containing 2 complete sets of chromosomes, one from each parent (2n). | |
DNA | Deoxyribonucleic Acid, a molecule that carries genetic information for a developing and functioning organism. | |
Double Helix | The shape and structure of the DNA strand. | |
Gametes Cells | Sex cells, a haploid cell. | |
Haploid | A single set of unpaired chromosomes (n). | |
Histones | Hydrogen Bonds | A weak bond between 2 molecules, but the large numbers provide crucial stability for the DNA strand.
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Interphase | A phase where G1, S1, and G2 occurs, before Mitosis or Meiosis (PMAT). | |
Major Groove | The wider space between the two strands of the DNA double helix. | |
Meiosis | A type of cell division that results in 4 unique daughter cells, and primarily only for gametes. | |
Metaphase | The second stage of cell division, where spindle fibers attach to the centromere of the chromosomes. | |
Methyl | A “tag” that causes DNA to wrap tighter around nucleosomes, which “turns off” the gene, causing decreased gene expression. | |
Minor Groove | The narrower space between the two strands of the DNA double helix. | |
Mitosis | A type of cell division that results in 2 identical daughter cells, and primarily only for somatic cells. | |
Nitrogenous Base | Adenine pairs with Thymine Adenine pairs with Uracil (RNA only) | |
Nucleosomes | Groups of proteins that DNA wraps around | |
Nucleotide | The organic molecules that make up a Nitrogenous Base. (Phosphate and Deoxyribose). | |
P-Arm | The short arm of a Chromosome | |
Phosphate | PO4 → A key component in the DNA molecule’s backbone along with Phosphate | |
Prophase | The first stage of cell division where the chromosomes become visible as paired chromatids. | |
Q-Arm | The long arm of a Chromosome | |
Single Strand | Typically associated with RNA |
Sister Chromatids | Identical copies of a chromosome that are held together during replication. |
Somatic Cells | Body cells, a diploid cell. |
Telophase | The fourth/final stage of cell division, where 2 new nuclei are formed. |
5-prime end | 5th carbon of deoxyribose sugar ring, what phosphate bonds to. |
3-prime end | 3rd carbon of deoxyribose sugar ring |
Dehydration Synthesis | A chemical reaction involving removing a H2O molecule (water) from two molecules, to create a bigger molecule. |
Hydrolysis | A chemical reaction where a molecule is broken down by a reaction with a H2O molecule (water). |
Helicase | An enzyme that breaks the hydrogen bonds in a DNA strands. |
DNA polymerase (DNAP) | An enzyme that builds the polymer of DNA by adding onto only the 3’ end because we read DNA 5’ to 3’. |
Leading Strand | “Good guy strand.” Adds DNAP smoothly, because the DNAP can just follow the helicase. |
Lagging strand | “Scumbag strand.” A strand that’s 3’ to 5’, so the DNAP can only add on in small sections since it can’t follow the helicase. |
Ligase | An enzyme that “glues” together all the segments of DNA, and checks over the patterns. |
Primase | An enzyme that lays down a small little RNA primer to get the DNA replication started. |
Polymers | Repeating monomers |
Base Sequence | AT || GC AU (RNA only) |
RNA | Ribonucleic Acid is single stranded, and has ribose sugar. Thymine is replaced with Uracil. |