Exam 2 Top 300

ropinirole brand

Requip

ropinirole class

dopamine agonist

ropinirole use

parkinson's, restless leg syndrome

ropinirole moa

stimulates dopamine receptors

ropinirole dose

IR: 0.25-8 mg PO TID, ER: 2-24 mg PO qD

ropinirole contraindications

avoid abrupt withdrawal

ropinirole bbw

none

carbidopa & levodopa brand

Sinamet

carbidopa & levodopa class

anti-parkinson's agent, decarboxylase inhibitor, dopamine precursor

carbidopa & levodopa use

parkinson's

carbidopa & levodopa moa

inhibits peripheral dopamine decarboxylation, dopamine precursor

carbidopa & levodopa dose

individualized

carbidopa & levodopa contraindications

MAO inhibitor use, psychosis, angle-closure glaucoma, avoid abrupt withdrawal

carbidopa & levodopa bbw

none

pramipexole brand

Mirapex

pramipexole class

dopamine agonist

pramipexole use

parkinson's, restless leg syndrome

pramipexole moa

stimulates dopamine receptors

pramipexole dose

IR: 0.5-1.5 mg PO TID, ER: 0.375-4.5 mg PO qD

pramipexole contraindications

avoid abrupt withdrawal

pramipexole bbw

none

donepezil brand

Aricept

donepezil class

cholinesterase inhibitor

donepezil use

Alzheimer's

donepezil moa

reversibly binds to and inactivates acetylcholinesterase

donepezil dose

5-10 mg PO qHS

donepezil contraindications

none

donepezil bbw

none

memantine brand

Namenda

memantine class

NMDA receptor antagonist

memantine use

dementia, Alzheimer's

memantine moa

binds to NMDA receptors, may slow calcium influx and nerve damage

memantine dose

IR: 10 mg PO BID, ER: 28 mg PO qD

memantine contraindications

none

memantine bbw

none

carbamazepine brand

Epitol, Tergretol

carbamazepine class

anticonvulsant

carbamazepine use

seizure disorder, trigeminal neuralgia

carbamazepine moa

reduces post-tetanic potential, decreasing seizure spread

carbamazepine dose

IR: 800-1200 mg qD divided BID or QID, ER: 400-600 mg PO BID

carbamazepine contraindications

hypersensitivity to TCAs, MAO inhibitor use, bone marrow depression, avoid abrupt withdrawal

carbamazepine bbw

risk of severe blood disorders and dermatological reactions

divalproex sodium brand

Depakote

divalproex sodium class

anticonvulsant

divalproex sodium use

partial seizures, absence seizures, bipolar disorder, migraine

divalproex sodium moa

increases GABA effects, may inhibit glutamate/NMDA receptor mediated neuronal excitation

divalproex sodium dose

individualized

divalproex sodium contraindications

angioedema, pregnancy

divalproex sodium bbw

may increase risk of hepatotoxicity and pancreatitis, may cause birth defects

levetiracetam brand

Keppra

levetiracetam class

pyrrolidine anticonvulsant

levetiracetam use

partial and tonic/clonic seizures

levetiracetam moa

selectively prevents synchronization of epileptiform burst firing

levetiracetam dose

IR: 500-1500 mg PO/IV q12h, ER: 1000-3000 mg PO qD

levetiracetam contraindications

avoid abrupt withdrawal

levetiracetam bbw

none