anatomy
study of the structure of body parts and their relationship to one another
physiology
study of the function of body parts; how they work to carry out life-sustaining activities
chemical level
atoms, molecules, and organelles
cellular level:
single cell
tissue level
groups of similar cells
organ level
contains two or more types of tissues
organ system level
organs that work closely together
organismal level
all organ systems combined to make the whole organism
requirements for life
movement, responsiveness, digestion, metabolism, excretion, reproduction, and growth
what is resposiveness
ability to see and respond to stimuli
digestion
breakdown of ingested food, followed by absorption of molecules into blood
metabolism
all chemical reactions that occur in body cells, sum of all catabolism (breakdown of molecules) and anabolism (synthesis of molecules)
excretion
removal of wastes from metabolism and digestion; urea (from breakdown of proteins), carbon dioxide (from metabolism), feces (unabsorbed foods)
reproduction
at the cellular level, reproduction involves division of cells for growth or repair. at organismal level reproduction is the production of offspring
growth
increase in the size of a body part or organism
survival needs
nutrients, oxygen, water, normal body temperature, appropriate atmospheric pressure
nutrients
chemicals for energy and cell building; (carbohydrates, proteins, fats, minerals, and vitamins)
oxygen
essential for release of energy from foods; the body can only survive for a few minutes without oxygen
water
most abundant chemical in body; provides the watery envioroment needed for chemical reactions; fluid base for secretions and excretions
normal body temp
if body temp falls below or goes above 37 degrees celsius, rates of chemical reactions are affected
appropriate atmospheric pressure
specific pressure of air is needed for adequate breathing and gas exchange in lungs
Parts of homeostatic control system
sensor, controller, effector
sensor (receptor)
monitor internal and external environment; respond to stimuli (things that cause changes in controlled variables)
controller (control center)
determine set point at which a variable is maintained, receive input from sensor, determine appropriate response
effector
receive output from control center, provide the means to respond, response either reduces stimulus (negative feedback) or enhances stimulus (positive feedback)
negative feedback mechanism
insulin regulating blood sugar and kidneys regulating electrolyte balance
positive feedback mechanisms
very rare in the body, labor through release of oxytocin and platelet recruitment/clotting after injury
sagittal plane
splits body into right and left sections
frontal/coronal
splits body into ventral/dorsal sections
transverse
splits body into superior/inferior sections
what makes up the dorsal body cavity
cranial and vertebral
what makes up the ventral body cavity
thoracic and abdominopelvic
serous fluid
prevents friction between membranes
pleural membrane surrounds
lungs
peritoneal membrane surrounds
abdominopelvic cavity
pericardial membrane surrounds
heart
what cavities are exposed to the external environment
digestive (oral and anal), nasal, orbital, and middle ear cavities
monomer, function, and types of Carbohydrates
monomer= simple sugars like glucose elements= C,H,O functions= first source of energy can be stored as glycogen in animals and starch in plants types= glycogen, starch, cellulose, chitin
monomer, function, and types of lipids
monomers= fatty acids, glycerols functions= long-term energy storage, insulation, cushioning, steroids types= phospholipids, triglycerides, steroids like cholesterol, hormones
saturated fats are
solid at room temp because they only contain single carbon-hydrogen bonds, allowing chains to be more compact (tight)
unsaturated fats are
liquid due to double bonds in structure that cause "kinks" in chains and require more space between molecules (loose)
monomer, function, and types of proteins
monomer= amino acids functions= movement, structure, transport, hormones, enzymes types= globular and fibrous
globular proteins have what structure
3D structure
primary level of protein structure
linear sequence of amino acids
secondary level of protein structure
the result of primary amino acids interacting; alpha helices and beta pleated sheets
tertiary level of protein structure
the result of secondary structures (helices and sheets) interacting
quaternary level of protein structure
how two or more polypeptides interact with each other
denaturation
occurs when pH or temp is changed; permanent if extreme
enzymes
speed up the rate of chemical reactions by lowering the activation energy at which reactions occur, require specific temperature and pH to function (could perhaps expect a figure/graph related to this)
monomer, function, and types of nucleic acids
monomer= nucleotides (made up of phosphate, sugar, and nitrogen base) functions= store and transmit genetic info types= DNA and RNA
ATP (adenosine triphosphate)
composed of adenine + ribose and 3 phosphate groups; energy is released when high energy bond between the last two phosphate groups is broken; energy can be "added" back by reforming the bond and reattaching a phosphate group; when one phosphate group is lost ADP forms when two or are lost AMP is formed
prokaryotic cells
no nucleus, DNA is in nucleoid region, no membrane bound organelles, only ribosomes, have a flagellum
eukaryotic cells
DNA in nucleus, several membrane bound organelles contribute overall function of the cell
ribosomes
protein synthesis; found on RER and in cytosol
cell membrane
semi permeable, barrier inside/outside, transport
mitchondrion
metabolic activities including cellular respiration (produces ATP)
nucleus
contains DNA, site of DNA replication and transcription
golgi apparatus
protein packaging for transport
vesicle
transport of proteins and other molecules between organelles
rough ER
dotted with ribosomes, functions in protein synthesis
lysosome
sac containing enzymes to breakdown and recycle biomolecules
smooth ER
synthesizes lipids, metabolizes carbs, clears drugs/toxins
parts of cell membrane
phospholipids, proteins, cholesterol
phospholipids
polar heads that are hydrophilic, nonpolar tails that are hydrophobic; form a phospholipid bilayer
proteins
integral (transmembrane) embedded in membrane and span all the way across from inside cell to outside; peripheral- attached to the outside or inside of the cell
cholesterol
form steroid hormones, regulate fluidity of cell membrane- more cholesterol = more rigid
fluid mosaic model
parts of the membrane are freely moving can't flip without flippase/floppase/scramblase enzymes
passive transport
doesn't require ATP
simple diffusion
movement of molecules from an area of high concentration to an area of lower concentration down a concentration gradient
osmosis
movement of water molecules from an area of high concentration to an area of lower concentration down a concentration gradient
isotonic
the same concentration of solutes as another solution
hypertonic
solute concentration is higher outside the cell than inside the cell, cell shrinks
hypotonic
solute concentration outside the cell is lower than inside the cell, cell swells
facilitated diffusion
proteins (channel or carrier) are used to move molecules from an area of high concentration to an area of lower concentration down a concentration gradient
active transport
requires ATP; endocytosis and exocytosis
transport proteins
use of proteins to move molecules from an area of low concentration to an area of high concentration against a concentration gradient
endocytosis
movement of large materials into the cell
exocytosis
movement of large materials out of the cell
hemidesmosome
attaches cell to basal lamina of ECM
desmosome
attaches cell to cell and provide elasticity
adherins junction
attaches cell to cell with a stable anchoring point
tight junction
attaches cell to cell, prevents paracellular diffusion
gap junction
attaches cell to cell and establishes a passageway
transcription
converting DNA into mRNA; DNA is trapped in nucleus and must be transcribed into single-stranded mRNA, pre-mRNA must be processed into mRNA by splicing out introns and addign 5' caps and poly A tails
translation
converting mRNA into proteins; mRNA attaches to ribosomes (made of rRNA and proteins), tRNA brings amino acids to the ribosome during translation
apical
exposed to surface or lumen
basolateral
between cell-to-cell or cell-to-basement membrane
basement membrane
separates epithelium and connective tissue underneath
epithelial tissue cell types
squamos- flat; cuboid- cube shaped; columnar- column shaped
simple squamous tissue
thin, single layer of cells, found in alveolar sacs, capillaries, etc.
pseudostratified columnar tissue
single layer that appears as 2 layers, contains goblet cells that secrete mucus
transitional tissue
cells flatten/thin out to allow for stretch, commonly found in bladder
endocrine glands
ductless, secrete hormones into capillaries
exocrine glands
have ducts in which products are secreted; merocrine, apocrine, holocrine
merocrine
secrete through exocytosis (salivary)
apocrine
secrete by pinching off portions of membrane (mammary)
holocrine
secrete by rupturing the cell (sebaceous/oil)
connective tissue functions
protection, structural support, energy storage, insulation, and transport substances within the body
connective tissue fibers
collagen, elastin, reticulin
collagen
bundles, resist tension