CPJE 2025 Practice Exam | Realistic Questions & Answers New Update

Rotigotine

Neupro patch: do not heat/ use during MRI

HLA b1502

Test in Asians. Rash for carbamazepine (tegretol), phenytoin (Dilantin), fos phenytoin (cerebyx)

Trastuzumab

Herceptin, her/Neu- ado-trastuzunab (kadcyla), lapatinib (tykerb) pertuzumab (perjeta)

Hla- b 5701

Don't give abacavir (ziagen), epzicom, trizivir

Not cross reactive a/ opioid allergy

Fentanyl, meperidine (Demerol), methadone (dolophine), tramadol (ultram), tapentadol (nucynta)

Inducers

Ps porcs (phenytoin, smoking, phenobarbital, oxcarbazepine, rifampin, carbamazepine, St. John's wort)

Inhibitors

Gpacman (grapefruit, pi's, azoles, cimetidine/cyclosporine, macrolides- erytho/clarithro, amiodarone, non dihydro (dilt, verapamil)

If on amiodarone, decrease these drugs by 30-50%

Digoxin, warfarin, quinidine, procainanide, statins

Statins with high risk of inhibition

Las (lova, atorva, simva)

Entecavir

Baraclude. Empty stomach for hep B that fail lamivudime and adefovir- se: peripheral edema, nephrotoxic

Ribavirin

Copegus. W/ food bid for hep c, hepatotoxic, hemolytic anemia, preg x, psych disorders, ci: renal disfxn

Glipizide

Glucotrol 30 min before break & dinner

Glimeprimide

Amaryl 1-2 mg qd w/ 1st meal

Glyburide

Diabeta, + metformin = glucovance, do not use w/ renal failure 2.5-5mg qd

Rosiglitazone

Avandia 4-8mg qd (tzd, exacerbate hf, liver damage, increases hdl, decreases tg/total cholesterol) similar: pioglitazone (actos)

Repaglinide

Prandin 0.5-2mg TID 15-30 min before a meal, hypoglycemia- do not take with su's

Nateglinide

Starlix injection- 15-30 min before meals

Acarbose

Precose- w/ 1st bite of meal and water

Miglitol

Glyset w/ 1st bite of meal and water

Linagliptan

Tradjenta- 5 mg qd in morning with or without food, no renal adjustment

Saxagliptin

OnglyZa 2.5-5mg qd

Canaglifozin

Invokana 100mg qd before first meal of day for DM. Se: female genital mycotic infxn, increased urination, hyperkalemia, can increase dig levels, ci: renal dx

Exenatide

Byetta 30-60 min before am & pm meals,medguide, pancreatitis, thyroid c-cell carcinoma xr= bydureon

Liraglutide

Victoza QD thyroid c-cell carcinoma, more weight loss, less pancreatitis

Pramlintide

Symlin - injection, skip if no meals, weight loss

Insulin aspart

Novolog rapid

Insulin glulisine

Apidra rapid

Insulin lispro

Humalog rapid

Detemir

Levemir long acting

Insulin glargine

Lantus long acting

Ibandronate

Boniva 150 monthly

Zolendrenic acid

Reclast iv - pretreat w/nsaids

Teriparatide

Forteo SC daily: osteosarcoma, kidney stones, orthostatic hypotension, hypocalcemia- must take ca starting 2 weeks before time- fridge after each dose, sit while giving

Lotensin

Benazepril

Indapamide

Lozol 1.25-5mg- thiazide diuretic

Aerobid

Budesonide inhaler

Invirase

Saquinavir tabs (fortivase=soft gels)- BID with food & norvir, pi= lipodystrophy, hepatotox

Budesonide

Plumicort inhaler/ rhinocort

Triamcinolone

Azmacort inhaler, nasacort nasal

Selegiline

Eldepryl 5-10mg qd,Mao-I for Parkinson's, requires medguide or ensam patch for depression

Dalteparin

Fragmin (lmwh) ci: pork allergy, no antidote, affects anti-xa

Metolazone

Zaroloxyn, diuretic, allows for use of other thiazides in renal impairment

Captopril

Capoten (acei) 25 bid-TID 1 hour before meals- taste disturbances, preg x

Mevacor

Lovastatin

Pindolol

Visken

Fosamprenavir

Lexiva bid-TID, sulfa drug, susp= empty stomach for adults, kids with food

Emtricitabine & tenofovir

Truvada - pigmentation, fanconi, problem absorbing electrolytes

Zidovudine/ lamivudine

Combivir bid- pigment, pancreatitis

Tiprinavir

Aptivus- bid w/ food, sulfa, separate from antacida

Ticlopidine

Ticlid, p2y12 inhib like clopidegrel- se: sjs, ttp (thrombocytopenic purpurea)

Moexipril

Univasc ace

Perindopril

Aceon

Ramipril

Altace

Trandopril

Mavik

Fosinopril

Monopril

Eprosartan

Teveten

Azilsartan

Edarbi

Atazanavir

Reyataz qd, nephrolithiasis (take with water), separate from ppi's/h2ra's

Didanosine

Videx qd (empty stomach), pancreatitis

Tenofovir

Viread qd fanconi syndrome, treats hep b

Almotriptan

Axert

Eletriptan

Relpax

Frovatriptan

Frova

Naratriptan

Emerge

Peglioticase

Krystexxa (iv refractory only for gout), anaphylaxis during infusion require premed w/ antihistamines

Bp goal

<140/90 unless dm or ckd then <130/80

Chlorthiazide

Diuril- thiazide, hyperglycemia, hyperlipidemia, sulfa

Ethacrynic acid

Edecrin- most ototox, sulfa, gout, photosensitive

Triamterene

Dyrenium

Amiloride

Midamor k sparing

Eplerenone

Inspra- good for class 3 & 4 heart failure

Aliskerin

Tekturna - preg x, renin- inhib for htn

Metoprolol tartrate

Lopressor w/ food

Acebutolol

Sectral

Bisoprolol

Zebeta

Nebivolol

Bystolic: nitric acid dilation properties, hypertriglyceride, decrease hdl

Nadolol

Corgard

Labetalol

Trandate

Verapamil

Calan, covera- don't use w/ b- blocker, arrhythmias, gingival hyperplasia, no grapefruit, decrease hr/contraction

Felodipine

Plendil- reflex tachycardia, headache

Nifedipine

Adalat, procardia

Nicardipine

Cardene

Clevidipine

Cleviprex, iv ccb, do not use in soy/peanut allergy

Guanfacine

Tenex 0.5-2mg qd, alpha 2 agonist, do not stop abruptly

Methyldopa

Aldomet- 250 bid-TID, se: hsr, hep, myocarditis, lupus, anemia

Prazosin

Minipress- orthostatic hypotension, priapism, floppy iris syndrome

Lotrel

Amlod/benaze

Amlodipine/valsartan

Exforge

Amlodipine/olmesartan

Azor

Irbesartan/hctz

Avalide

Losartan/hctz

Hyzaar

Amiloride/hctz

Moduretic

Fluvastatin

Lescol

B blocker for hf

Metoprolol er, bisoprolol (zebeta), carvedolol (coreg)

Bidil

Isosorbide dinitrate/ hydralazine- good for AA for HF

Electrolyte imbalances increasing dig tox

Hypokalemia/magnesium/thyroid and hypercalcemia

Argatroban

Used in HIT, & renal impairment, increases iNr, monitor aptt, reduce in hepatic impairment, direct thromb inh

Dalteparin

Fragmin 2500-5000u sc daily, txt: 120u/kg bid

Darbigatran

Pradaxa- more gi ulceration/ bleeds, reduce if renal dx, discard after container is open >4 months, d/c 1-2 days before surgery- direct thrombin inh

Bivalrudin

Angiomax: reduce in renal failure, direct thrombin inh