Golgi Complex and Lysosomes

glycosylation

addition of carbs to proteins so P will work properly

GC

major site of new membrane synthesis where lysosomes and peroxisomes are formed

trans

part of GC that has the major protein content

cis, medial, trans

3 parts of GC

IGG

fights infections

IGE

fights allergies

lipoprotein

lysosomes are surrounded by what?

hydrolytic enzyme

what degrades the molecules that the lysosome ingests

suicide bag

sometimes the lysosome is termed as, because when it ruptures, lysosome enzymes such as ACID PHOSPHATASE might cause the whole cell to die

lysosomal stage disorders

enzymes to break down molecules does not function well so the molecules pile up until it causes organ damage

inclusion cell disease

no enzymes to break down molecules at all because GC fails to tag the enzymes as it should be so it does not reach the lysosome, cause developmental damage, most children with this condition die.

gout

too much uric acid (sharp) causes lysosomes to burst triggering inflammatory enzymes

tumor metastasis

when cancer uses CATHEPSIN a lysosome enzyme to break down other organs’ barrier so it can spread

silicosis

when inhaled, might cause lung lysosomes to burst causing lung inflammation and scarring

M6P

whats supposed to be in lysosome enzymes so it is “tagged properly” and make sure it is delivered to the lysosome