Anatomy and Physiology 1

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221 Terms

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Heart

Delivers oxygen

Delivers heat to the surface of the skin

Removes the waste products in the body

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Route taken by blood

RVAVAVAL

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Chambers of the heart

Right atrium, right ventricle, left ventricle left atrium separated by the septum

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Size and strength of chambers

Atriums have thin muscle walls

Ventricles have thick walls

Left side of the heart is larger

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Name and location of valves

Bicuspid separates left atrium and ventricle

Tricuspid separates right atrium and ventricle

Semi lunar valves separate ventricles and arteries

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Chordae Tendineae

Strong fibrous strings that attach heart muscles to the valves. They serve to anchor the valves and not let them close

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Cardiac Conduction system

A group of specialised cells located in the wall of the heart which send electrical impulses to the cardiac muscle, causing it to contract.

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SAN

Sino atrial node

Begins the wave of excitation

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Myogenic

Capacity of the heart to generate its own impulses

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What is the impulse described as

Wave of excitation

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AVN

Atrio ventricular node

Delays the wave of excitation to limit the increase of the Heart rate

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Systole and diastole

Heart pumping and the heart filling respectively

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What follows the AVN

Bundles of HIS, splitting into bundle branches

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What follows bundle of HIS

Purkinje fibres, these spread the impulses around the ventricles and cause them to contract

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Neural Control system

Central nervous system

Peripheral nervous system

Autonomic nervous system

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CNS

Brain

Retina

Spinal cord

Command centre of the body

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Peripheral nervous system

Nerves that connect the CNS to the arms and legs

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Autonomic nervous system

Nerves that connect the CNS to organs

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What is the autonomic nervous system split into

Sympathetic and Parasympathetic

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Sympathetic

A part of the nervous system that speed up heart rate and prepares the body for exercise

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Parasympathetic

Decreases heart rate and returns the body to a resting state after exercise

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Medulla Oblongata

Cardiac Control Centre

Responsible for autonomic nervous functions

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What is the medulla oblongata stimulated by

Chemoreceptors

Baroreceptors

Proprioceptors

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Chemoreceptors

Detect changes in the acidity and chemicals in the bloodstream

Increase in CO2 = increase in heart rate

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Baroreceptors

Detect changes in blood pressure

Increase in blood pressure= decrease in HR

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Proprioceptors

Detect changes in muscle movement and tension

Increase muscle movement = Increases HR

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Hormonal Control System

Adrenaline is released from the adrenal glands and mimicks the sympathetic nervous system increasing heart rate before exercise

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Stroke volume

The volume of blood pumped by the ventricles for each contraction

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Ejection fraction

The percentage of blood pumped out by the left ventricles per beat

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cardiac output

stroke volume x heart rate

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Venous return

Amount of blood returning to the lungs via the veins

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Starlings law

Increased venous return, increased diastolic filling, cardiac muscle is stretched, more force of contraction, increased ejection fraction

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Myocardium

Cardiac tissue

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Cardiac hypertrophy

The thickening of the muscular wall of the heart so it becomes stronger

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Bradycardia

A decrease in resting heart rate below 60bpm

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Coronary Heart Disease

Coronary arteries are blocked and lumen is narrow reducing blood flow

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Atherosclerosis/ atheroma

The process of fatty build ups being deposited in the vessels. Atheroma is the fatty deposits

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Angina

Chest pain when the coronary arteries are blocked enough to cause pain

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Blood Pressure

The force exerted by the blood on the walls of the blood vessels

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Cholesterol (LDL)

Low density lipoproteins

Transports cholesterol to the blood vessels. Considered the bad ones as linked to heart disease

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Cholesterol (HDL)

High density lipoproteins

Transport atheroma back to the liver where it is broken down. Considered the good ones as they lower the risk of CHD

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Ishaemic stroke

The most common. Occur when a blood clot stops blood supply

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Haemorrhagic Strokes

occur when a weakened blood vessels supplying the brain bursts

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Cardiovascular drift

Heart rate increases

Stroke volume decreases

Fluid is lost as sweat

Reduced plasma volume

Reduced venous return

Cardiac output also increases due to more energy needed to cool the body

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5 different types of blood vessels

Arteries

Arteriols

Capillaries

Venules

Veins

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Veins

Thinner muscle/ elastic tissue

Blood is at low pressure

Valves

Wider lumen

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Arteries

Thick muscle and elastic tissue

Small lumen

High blood pressure as they carry blood away from the heart

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Capillaries

One cells thick

Short diffusion path for oxygen and Co2

Very low blood pressure

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Systemic blood pressure

Pressure of the oxygenated blood travelling to the body

The pressure in the arteries when the heart is contracting

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Diastolic blood pressure

The pressure of the deoxygenated blood travelling from the heart to the lungs

The pressure in the arteries when the ventricles are relaxing

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Where is blood pressure measured from

The brachial artery in the upper arm

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What is a healthy blood pressure

120/80

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Three mechanisms for venous return

Skeletal muscle pump

Respiratory pump

Pocket valves

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Skeletal muscle pump

The muscles contracting and changing shape resulting in veins to change shape and squeeze the blood back to the heart

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Respiratory pump

The pressure changes in the thoracic and abdominal cavities during breathing and will therefore compress the nearby veins and push blood back to the heart

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Pocket valves

These valves prevent the back flow of blood in the veins

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Equation for blood pressure

Blood flow x resistance

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What is venous return determined by

Pressure gradient

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Mean systemic pressure

The mean pressure that exists in the circulatory system when the heart has had a chance to evenly redistribute blood to all vessels and organs

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Peripheral veins

Lead deoxygenated blood from the capillaries back to the heart

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Vascular resistance

The resistance that must be overcome for the blood to be pushed around the circulatory system

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Haemoglobin

An iron-containing pigment found in red blood cells, which combines with oxygen to form oxyhaemoglobin

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Myoglobin

Often known as muscles haemoglobin

Stores the oxygen in the muscles to be used during longer activities

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Mitochondria

Site for aerobic respirations and is the powerhouse of the cell

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High affinity for oxygen

Need lots of oxygen to operate

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What is the name for the translation of the curve in the positive x direction

BOHR shift

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What factors impact the BOHR shift

Increased temperature

Increased partial pressure of CO2

Lower pH (increased acidity)

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What is the redirecting of blood to the areas that need it called?

Vascular shunt mechanism

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What happens to the blood during vigorous exercise as a result of a vascular shunt?

Blood is distributed away from digestive organs and travels to the working muscles.

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Pre capillary sphincters

Rings of tissue at the start of the blood vessel. When contracting, they block of the proceeding vessel and there is limited blood flow to the areas that vessel supplies.When they contract blood flow is blocked.

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Vasodilations and Vasoconstriction

Dilation- the widening of the lumen to allow more blood flow. This also pushes the vessel closer to the surface to allow for heat to leave the body

Constriction- Vessels decrease lumen diameter and go deeper into the skin resulting in a conservation of heat

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Why is blood distribution important? (4 things)

Increase supply of oxygen

Remove lactic acid and other waste products

Regulation of body temperature

Direct more blood to the heart

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Atrio-venous difference

The difference between the content of oxygen of the arterial blood arriving at the muscles and the venous blood leaving the muscles

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At rest, what is the AVO2 like

Low as not much oxygen is required at the muscles

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What is the equation for venous pressure

Venous pressure - Right atrial pressure /Total peripheral vascular resistance

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The sections of vertabrae

Cervical, thoracic, lumbar, sacrum, coccyx

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Bones in the pelvis

Iliac crest

Ilium

Pubis

ischium

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Cervical vertabrae

7 bones

Provides support for the weight of the head and surrounds and protects the spinal cord

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Thoracic vertabrae

12 vertabrae

Provides attachment point for multiple muscles

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Lumbar vertabrae

5 vertabrae

Provides stability for the spinal column and back

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Sacrum vertabrae

5 vertabrae

Is fused to the coccyx and is responsible for strengthening the pelvis

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Coccyx

4 vertabrae

Fused to sacrum and provides weight bearing support when seated also multiple insertion point for muscles and ligament

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5 types of bones

Long

Short

Irregular

Flat

Sesamoid

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Long bone

Longer than it is wide

Femur, humerus, tibia, fibula

Shaft called diaphysis and ends called epiphysis

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Short bone

Cube shaped consisting of cancellous bone surrounded by a layer of compact bone

Carpals, Tarsals, Wrists

Fine or small movements, shock absorption, weight bearing

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Flat bone

Thin, flattened and slightly curved, with a large surface area.

Sternum, Cranium

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Irregular bone

Mostly protect the spinal cord and allow small amounts of movement

Vertabrae

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Sesamoid bones

Have a specialised function

Protection and reduction of friction at a joint

Patella

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Ligaments

Strong fibrous tissue

Stabilise the joint, attach bone to bone, prevent any unwanted movement

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Fibrous joint

Fixed position

Protects vital organs

Bones overlap and interlock

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Cartilaginous joint

Slightly moveable

Bones are separated by fibrocartilage which when compressed, will move bones

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Synovial joint

Freely moving

High level of mobility at the joint

Most of e body’s joints are synovial

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Functions of the skeletal system (PASS and MOVE)

Protection, Attachment, Blood cell production, Store of minerals, Movement

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Neuromuscular system

Nervous system and muscular system work together to allow movement

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Three different muscle fibres

1, 2a, 2x

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Type 1 muscle fibre

Small and red

Slow force of contraction and speed

Aerobics

High fatigue resistance

High mitochondria and high slow release sugars

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Type 2a fibres

Moderate and red

Medium force of contraction and speed

Aerobics

High fatigue resistance

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Type 2x fibres

Large and white

High force of contraction and speed

Weight lifting and sprinting

High glucose

Low fatigue resistanace

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Motor Unit

A motor neurone and its muscle fibres

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Motor neurones

Nerve cells which transmit the brains instructions as electrical impulses to the muscles