WK11 Recombination

Flashcards based on lecture notes covering recombination, linkage mapping, and genetic markers.

Recombination

The reassortment of genes/alleles into combinations different from those of the parents as a result of independent assortment.

Linkage

Refers to the closeness of genes on the same chromosome. When genes are linked, they are close by and are inherited together avoiding Mendel's rules of independent assortment.

Genetic Map

Diagram showing the relative locations of genes along a chromosome.

CentiMorgan (cM)

A unit of measure for genetic linkage. One centiMorgan is equivalent to a 1% recombination frequency.

Independent Assortment

Mendel's law stating that the inheritance of one pair of factors (genes) is independent of the inheritance of the other pair, applicable only if the genes are on separate chromosomes.

Dihybrid Testcross

A cross between an F1 individual and the homozygous recessive parent, used to test for independent assortment.

Recombination Frequency

The proportion of offspring that exhibit recombinant genotypes. It is used to estimate the distance between genes on a chromosome.

Parental Types

Progeny that exhibit the same allelic combinations as their parents; these typically have a higher frequency when there is genetic linkage.

Recombinant Types

Progeny that exhibit different allelic combinations compared to their parents, resulting from recombination events.

SNPs (Single Nucleotide Polymorphisms)

Single base pair alleles that can be used as co-dominant markers in genetic mapping.

Marker Loci

Well-characterized locations on the genome used in recombination mapping to locate genomic regions that affect phenotypes.

Genetic Distance

The distance between genes measured in centiMorgans (cM), which is based on recombination frequency.