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functions of the cell
metabolism, synthesis, communication, reproduction and inheritance
basic composition
cell membrane, cytoplasm, organelles, nucleus
cell membrane
plasma membrane consists of phospholipid bilayer with proteins and cholesterol molecules dispersed within
separates intracellular and extra cellular materials
membrane potential
production of charge difference across membrane by regulation of intracellular and extra cellular ion concentrations
fluid mosaic model
phospholipid units reassemble if membrane is damaged
integral proteins
act as channel
peripheral proteins
attached to only one side of membrane
attachment proteins
attach cells to other cells or molecules
channel proteins
non gated ion channels, always integral and open
gated, voltage or ligand depending, sometimes closed always integral
carrier proteins
transporters
have specific binding sites and change shape to transport ions/molecules
receptor proteins
attach to specific chemical signal molecules and act as intercellular communication system
ligands can only attach to cells with specific receptors
lock and key
passive transport
movement doesnt require energy
2 forms:
simple diffusion, higher to lower concentration
facilitated diffusion, higher to lower with help from membrane proteins
active transport
movement requires energy (atp)
lower to higher concentration
rate depends on atp
osmosis
diffusion of water, lower solute to higher solute concentration
hypotonic solution
less solute on outside of cell membrane, water enter cells (cell swells-lysis)
hypertonic solution
more solute on outside of cell membrane, cell shrinks (crenation)
isotonic solution
equally distributed solute on either side of cell membrane
optimal for cell function
filtration
depends on pressure difference on either side of a membrane
moves from side of greater pressure
endocytosis
internalization of substances by formation of a vesicle
2 types
phagocytosis - cell eating
pinocytosis - cell drinking
exocytosis
substances being expelled
cytoplasm
cell filler outside nucleus but inside plasma membrane
composed of cytoskeleton (microtubules/microfilaments) and cytosol (fluid portion)
essential
mostly water
endoplasmic reticulum
system of membranes that make up cisternae
rough er and smooth er
rough er
facilitates protein synthesis
ribosomes made of rna
made from outer shell nucleus
smooth er
manufactures and transports fats and lipids
calcium storage
detox
sex hormone synthesis
ribosomes
rna containing bodies
prod in nucleolus
protein synthesis
golgi apparatus
flattened membrane sacs stacked on each other
function- modification, packaging, sorting out, and preparing proteins and lipids for distribution (secretion or internal)
post office
mitochondria
powerhouse of cell
cristae: inner folds where cellular respiration occurs
higher need for atp, more mitochondria
lysosomes
tiny sacs filled with digestive enzymes
digest stored nutrients
help break down dysfunctional structures (waste/byproducts)
centrioles
located in centrosome (specialized zone near nucleus)
center of microtubule info
forms spindle fibers during cell division
guide duplicated chromosomes to form identical daughter cells-must split evenly
microvilli
cell membrane projection
multiple extensions of plasma membrane which do not move
increase surface area
cilia
cell membrane projection
fine hair like capable of movement extensions from cell membrane
multiple per cell
move materials across cell surface
like moving belt
flagella
cell membrane projection
similar to cilia but longer and single
propel the whole cell in wave like fashion (tail)
nucleus
organelle
control center of cell w dna
membrane has pores to allow passage of substances
chromatin
genetic material inside nucleoplasm is finely dispersed during state of rest
chromosomes
during cell division, chromatin condenses and forms tiny structures
same material assembled differently
nucleolus
site of ribosome formation
transcription
dna info being copied
mrna formed
translation
mrna directs new protein synthesis
converting copied info into protein
gene
functional unit of heredity
each gene occupies a specific place within chromosomes- locus
structural, template for mrna, code for amino acid sequences
regulatory, control which structural genes transcribed in given tissue
genotype
actual set of alleles a person has for a given trait
phenotype
persons appearance
allele
different forma of same gene
homozygous
2 of same allele for a trait
heterozygous
one dominant one recessive
karyotype
map of chromosomes
genetic disorders
abnormalities in dna
congenital disorders
birth defects not necessarily genetic
teratogens, agents that cause birth defects
mutation
mutagens, agents that cause mutations
cancer
tumor resulting from uncontrolled cell division
oncogenes, genes associated with cancer, tumor supression
interphase
in between 2 divisions
mitosis, prophase
nuclear envelope disintegrates, chromatin condenses, formation of chromosomes
mitosis, metaphase
chromosomes are aligned at the nuclear equator
mitosis, anaphase
chromatids separate and form chromosomes (2 identical sets)
mitosis, telophase
chromosomes decondense, nuclear envelope reforms, cytokinesis continues
cytokinesis
division/separtion of the cytoplsm, formation of two separate but identical daughter cells, separate process from mitosis