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Limitation to cell size
surface area to volume ratio (affects distance and so diffusion rate)
Specialised structures to increase surface area
folds, microvilli, flattened or elongated cells - all increase SA to V ratio
What happens to cells that are too large (SA:V)?
cells divide
Chemicals regulating cell growth
growth factors (proteins which regulate cell growth and survival)
Chemicals regulating mitosis
mitogens (peptides or small proteins that cause cells to enter mitosis by binding to receptors on plasma membranes)
Exceptions to normal cell cycle
grow without dividing (neurons, fat, muscle fibres) vs divide without growing (fertilised egg cell)