Temperature and Acid Base Management
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10 Terms
What are the protective effects of hypothermia?
Reduces metabolic rate and O2 consumption
Reduces excitatory neurotransmitter release
Slows down enzymatic reactions
Decreases inflammatory response to cardiopulmonary bypass
Chart of Hypothermia levels and circulatory arrest
What does hypothermia allow for in cardiac surgery?
Better pump flow
Myocardial protection
Less blood trauma
Organ protection
What causes the solubility of CO2 to increase?
Hypothermia
Why does pH increase during hypothermia?
Influence of buffers
What does hypothermia lead to?
Alkalosis and hypocarbia (reduced CO2)
What is alpha stat management?
Acid base management strategy that allows pH to ride and PCO2 to fall to match the temperature induced changes rather than adding CO2 to correct it
What is pH stat management?
pH remains constant as temperature changes by adding 5% CO2 to the system to maintain pH
What is the best way to protect the brain with acid base management?
pH stat during initial cooling phase
alpha stat strategy during reperfusion, rewarming and termination of CPB
What are the comparisons between the acid base management systems?
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