Countercurrent Mechanism

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Last updated 3:59 PM on 11/21/25
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5 Terms

1
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How does osmolarity change in the L.O.H?

  • descending limb = 300

  • base = 1200

  • ascending = 100

2
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What is the descending L.O.H. role?

  • supplied NaCl to ascending limb and diffuses H2O to increase osmolarity 

3
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What is the ascending L.O.H role?

  • transports NaCl into interstitium to increase concentration inside tubule

4
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What is the role of the Vasa Recta?

  • set of capillaries around L.O.H

  • blood down descending loses H2O to interstitial and gains higher NaCl concentration

  • blood up ascending regains water and loses NaCl

    • net result = blood brought nutrients to cell w/o washing away gradient

5
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Late filtrate processing in DCT

  • only occurs in precents of hormones

  • aldosterone for Na+

  • ADH for water