W11 Review - HES 105

T or F? Vo2 increases when arteriovenous difference decreases.

F

Compared to the amount of O2 dissolved in plasma, ______ O2 is typically bound to hemoglobin.

a lot more

Which pressure gradient establishes the driving force for diffusion of O2 at the lungs?

Alveolar to venous Po2

Which pressure gradient establishes the driving force for diffusion of O2 at the exercising muscles?

Arterial to tissue Po2

What is typically greater at rest?

Inspired PO2, PaO2

What is typically greater during maximal exercise?

PAO2

When is the time available for diffusion at the lungs greater?

at rest

For a given Po₂, what happens to So₂ with a right-shifted oxyhemoglobin curve?

So₂ will be lower.

With a right-shifted oxyhemoglobin curve, it takes a ______ Po₂ to achieve the same So₂.

Higher

A right-shifted oxyhemoglobin curve means Hb has a ______ affinity for O₂.

lower

With a right-shifted curve, is it easier or harder for Hb to unload O₂ at the tissues?

easier

With a right-shifted curve, how is Hb's ability to load O₂ at the lungs affected?

about the same

What is the main way we increase arteriovenous difference during exercise?

decreasing CvO2

Where does the hyperventilatory response at max exercise facilitate diffusion?

lung

What does the hyperventilatory response at max exercise increase?

alveolar-to-arterial PO2 gradient

Where does increased tissue O2 consumption at max exercise facilitate diffusion?

muscle

What does the increased tissue O2 consumption at max exercise increase?

aterial-to-tissue PO2 gradient

What is responsible for lowering SvO2 at max exercise?

increased temperature, CO2, and acidity