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monkeypox
recent epidemic/pandemics, 2022-present
nipah virus
recent epidemic/pandemics, 2023, India
listeria
bacteria, deli meats and unpasteurized milk, individuals age 65 and older and pregnant women most at risk
nipah virus
current epidemic in India, first discovered in 1999 following an outbreak of disease in pigs and people in Malaysia and Singapore
300 human cases and more than 100 deaths
morbidity and mortality of nipah virus
more than 1 million pigs killed to help control outbreak
economic impact of nipah virus
fruit bat
animal host reservoir for NiV
acute respiratory infection and fatal encephalitis
severe symptoms of infection from Nipah virus
true
direct contact with an individual with nipah can also lead to transmission, although this route is less common
40% to 100%
the case-fatality rates in outbreaks across Bangladesh, India, Malaysia, and Singapore typically range from ___ to ____
no
are there available effective therapies or vaccines for nipah?
discarded
fruit with signs of bat bites should be ____
washing and peeling fruit before consumption
ways to prevent contaminated fruit
99,518
cases of monkeypox globally in 2022
32,063
cases of monkeypox in the US in 2022
54
number of deaths from monkeypox in the US in 2022
monkeypox
rare disease caused by infection with the monkeypox virus, part of the same family of viruses as the variola virus (the virus that causes smallpox), symptoms are similar to smallpox symptoms but milder, rarely fatal, not related to chickenpox
1958
monkeypox was discovered in ___ when two outbreaks of a pox-like disease occurred in colonies of monkeys kept for research
1970
first human case of monkeypox was recorded in __
38%
percent of people who had monkeypox who also had HIV
41%
percent of people who had monkeypox but also had an STI in the past year
61%
percent of people who had monkeypox and also had either HIV or an STI
higher
the new epidemic of monkeypox in the democratic republic of the congo seems to have a ___ case fatality rate
15%, 19%
in 2016, communicable diseases accounted for about __ of all deaths globally and __ of disability-adjusted life years (DALYS)
40%, 40%
in low income countries, communicable diseases accounted for about __ of all deaths and __ of all DALYS
1.6 million, 940,000, 425,000
in 2017, TB was responsible for __ deaths, HIV/AIDS killed about _ people, and malaria killed __
525,000
in 2016, diarrhea killed about _ children under age 5
bacteria, viruses, or parasites
communicable disease may be caused by a wide variety of organisms, such as
leading, all ages
for many countries, communicable diseases were the __ cause of death and disability among __, but especially among the young and the old, can also cause great epidemics and become endemic and become routine causes of death
smallpox, 300 million, 500 million, 15 million
estimated to have killed up to __ people in the 20th century and around __ people in the last 100 years of its existence. as recently as 1967, __ cases occurred a year
virus
smallpox is caused by a
1918 influenza
killed 50 million people worldwide, in comparison, WWI killed 16 million lives
virus
1918 influenza is caused by a
bacteria
tuberculosis is caused by a
11 million
number of people living with TB
9 million
number of new TB cases
1.5 million
number of TB deaths
3.5%
proportion of new cases with multidrug-resistant TB
435,000, 403,000, 80%
it was estimated that ___ deaths due to malaria had occurred globally, of which ___ deaths (approx. 93%) were in the WHO African Region. almost ___ of deaths in 2017 occurred in 17 countries in the WHO African Region and India
parasite
malaria is caused by a
malaria
leading cause of DALYs in sub-Saharan Africa among all age groups
ischaemic heart disease, stroke, lower respiratory infections
top three leading causes of death globally
heart disease, cancer, covid-19
top three leading causes of death
barrier protections, immunizations, screening and case finding, treatment and contact treatment, efforts to maximize effectiveness of treatments and prevent resistance to treatment
public health tools that are available to address the burden of communicable diseases
HIV, STDs, tuberculosis, syphilis
screening controls the spread of many infections like
case finding
screening for communicable disease has been linked with
foodborne, waterborne, sexual or bloodborne, vector-borne, inhalation, non-traumatic contact, traumatic contact
transmission paths for communicable diseases
reservoir, humans, animals, and the environment
the habitat in which the agent normally lives, grows, and multiplies, include ___, ___, and ____
portal of exit
the path by which a pathogen leaves its host, usually corresponds to the site where the pathogen is localized
direct transmission
involves physical contact between humans, or close contact, skin to skin, droplets
indirect transmission
the transfer of an infectious agent from a reservoir to a host by suspended air particles, inanimate objects (vehicles), or animate intermediaries (vectors), airborne (measles)
fomites
inanimate objects such as handkerchiefs, bedding, or surgical scalpels
vehicles
may indirectly transmit an infectious agent include food, water,, biologic products (blood), and fomites
vectors
____ such as mosquitoes, fleas, and ticks may carry and infectious agent through purely mechanical means or may support growth or changes in the agent
reservoir, portal of exit, mode of transmission, portal of entry, susceptible host
chain of infection
92.1%, 91.7%
more people had health insurance in 2022 (___) than in 2021 (___), according to the US census bureau
were less likely
hispanic and black working-age adults ____ to have healthcare coverage than white/non-hispanic or asian adults in 2022
skipped doses of medicine, cut pill in half or not filled a prescription
nearly 25% of adults reported that either they or a member in their household has _____ in the last year due to cost
65.6% of insured adults having a private healthcare
private health insurance was more prevalent than public health insurance in 2022, with ______ plan compared to 36.1% having a public healthcare plan
employment-based health insurance, 54.5%
the most common subtype of health insurance coverage, covering ___ of the american population
medicaid and medicare, 18.8% and 18.7%
the second most common subtype of health insurance in 2022, covering ___ and ___ of the population
affordable care act, 9.9%
direct-purchase healthcare, such as ___ plans, covered ___ of the population
last
an assessment of 11 countries by the common wealth fund, ranked the US ____
4.3 trillion
the us spends approx. ___ per year on health care (2021)
18.3%
healthcare is ___ of the us gdp
$12,914
us spends ____ per person per year
10%
other developed countries generally spend about half as much per person and __ or less of their gdp
100 million
in the past five years, ___ report they’ve gone into debt because of medical or dental bills, the kff poll found (US)
$5,000
a quarter of adults with health care debt owe more than ___
1 in 5
about ___ with any amount of debt said they don’t ever expect to pay it off
medical bills
the largest reason for declaring bankruptcy in the US
confusing, doesn’t cover all citizens, expensive, don’t know what will be covered, administrative costs are over the top
challenges of the us system
administrative costs
the costs incurred by health plans, hospitals, providers, and other entities to conduct the business side of health care; including billing, enrollment, marketing, provider and medical management, member relations and corporate services
government-financed, employment-based, health insurance exchanges
types of insurance
medicare
federal government program, primarily funded by payroll tax, provides for persons 65 years and older, disabled persons eligible for social security benefits, and those with end-stage renal disease, 50 million americans are eligible, 60 million expected in near future
medicaid
federal plus state program, designed to pay for health services for specific categories of poor people and other designated groups: the disabled, children, pregnant women, etc., covers nearly 50% of births, nearly 40% of children, and over 50% of all custodial nursing home care, provides for individuals in the designated groups who are below the federal poverty level, current level for a family of four is approx. $25,000 a year
low
the reimbursement rates to clinicians are often comparatively ____
health insurance exchanges
provide a competitive marketplace to help increase access and control the costs of health insurance
the affordable care act (obamacare)
plans are offered to patients through a website, plans are split into medals, platinum, gold, silver, bronze, cost of plans are based upon: income, number of children, age, smoking status, and geography, removed pre-existing conditions, can remain on till age 26
the global fund
a worldwide partnership to defeat HIV, TB, and malaria and ensure a healthier, safer and more equitable future for all
5 billion a year, 100 of the hardest hit countries
the global fund raises and invests more than ___ to fight deadly infectious diseases, challenge the injustice that fuels them, and strengthen health systems and pandemic preparedness in more than _____
do not have access
1 in 5 children globally ____ to lifesaving vaccines
millions of children missed vaccines
the covid-19 pandemic disrupted health services and ____
4 million deaths
about ____ worldwide are prevented by childhood vaccination every year
$52
each dollar spent on immunization saves ___ in low- and middle-income countries
50 million deaths
more than ____ can be prevented through immunization between 2021 and 2030
measles vaccination can save nearly 19 million lives, hep B vaccination can save 14 million lives
by 2030, it is estimated that
14.5 million
in 2023, over ____ children under the age of 1 did not receive basic vaccines (referred to as “zero-dose” children). this is nearlyy 2.7 million more than in 2019 before the start of the pandemic
low and middle income countries
almost all zero-dose children live in ___, primarily in africa and southeast asia
antimicrobials
medicines used to prevent and treat infectious diseases in humans, animals and plants, includes antibiotics, antivirals, antifungals, and antiparasitics
antimicrobial resistance (AMR)
occurs when bacteria, viruses, fungi and parasites no longer respond to antimicrobial medicines
become ineffective and infections become difficult or impossible to treat
as a result of drug resistance, antibiotics and other antimicrobial medicines ____, increasing the risk of disease spread, severe illness, disability and death
human activity
the emergence and spread of amr is accelerated by ____, mainly the misuse and overuse of antimicrobials to treat, prevent or control infections in humans, animals and plants
top global public health and development threats
antimicrobial resistance is one of the _____, it is estimated that bacterial amr was directly responsible for 1.27 million global deaths in 2019 and contributed to 4.95 million deaths
misuse and overuse
the ____ of antimicrobials in humans, animals and plants are the main drivers in the development of drug-resistant pathogens
all, all
amr affects countries in ___ regions and at ____ income levels. its drivers and consequences are exacerbated by poverty and inequality, and low and middle income countries are most affected
modern medicine
amr puts many of the gains of _____ at risk. it makes infections harder to treat and makes other medical procedures and treatments- such as surgery, c sections and cancer chemotherapy- much riskier
1 trillion additional healthcare costs by 2050, and 1 trillion to 3.4 trillion gdp losses per year by 2030
amr has significant economic costs, the world bank estimates that amr could result in us dollars _____