PRIONS

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7 Terms

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Prion

Misfolded protein

Lack nuclei

Extremely resistant to heat, proteases, desinfectants and irriadiation

Induce apoptosis

Intracerebral- spongiform encephalopathy

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Creutzfeld-Jakob Disease (MAD COW)

Neurodegenerative disease

Sporadic, Acquired or Inherited

Spongiform encephalopathy

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4 types of CJD

Familial

variant

Iatrogenic

Sporadic

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Familial CJD

mutation in PRNP gene

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Variant CJD

by eating cow meat

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Iatrogenic CJD

medical procedures, surgical equipment

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Other prion diseases

Kuru

Gerstmann-Straussler-Scheinker