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Anaphase
In which phase do the centromeres split and sister chromatids begin moving apart?
Telophase
What happens during telophase?
Apoptosis
Which process describes programmed cell death that is distinct from mitosis?
Anaphase
Identify the phase of mitosis in the image (on the right) and describe two key features of this phase.
Prophase
Identify the phase of mitosis in the image (on the left) and describe two key features of this phase.
Meiosis
Define meiosis.
Diploid chromosome number
What is the diploid chromosome number?
Haploid chromosome number
What is the haploid chromosome number?
End of meiosis I
What happens at the end of meiosis I?
End of meiosis II
What happens at the end of meiosis II?
Gametes
Meiosis only occurs in which type of cells?
Diploid human germ cell after meiosis I and II
A diploid human germ cell (2n = 46) enters meiosis. How many chromosomes and chromatids are present at the end of meiosis I and in each gamete after meiosis II?
Mitosis vs Meiosis
Compare mitosis and meiosis in terms of role, divisions, chromosome number, and genetic outcome.
Variation in meiosis
Define variation in terms of meiosis.
Sources of variation
What are the 3 sources of variation in meiosis?
Crossing over
When does crossing over occur and what happens?
Independent/random assortment
When does independent/random assortment occur and what happens?
Non-disjunction
When does non-disjunction occur and what happens?
Recombinant chromatid
What is a recombinant chromatid?
Synapsis and chiasma
Explain how synapsis and chiasma formation generate genetic variation.
Non-disjunction consequences
What are the consequences of non-disjunction? Name a human disorder caused by it.
Stem cells
What are stem cells?
Sources of stem cells
What are the sources of stem cells?
Totipotent
Which type of stem cell can differentiate into all cell types of the embryo and extra-embryonic tissues?
Cancer
Define cancer.
Tumour definitions
Define the terms tumour, malignant, metastasis, benign, carcinogen.
Benign vs malignant tumours
Compare benign vs malignant tumours.
Tumour suppressor genes
How can mutations in tumour suppressor genes cause cancer?
Early detection technologies
What technologies help early detection of cancers?
Spermatogenesis
Where does spermatogenesis occur and what is its role?
Spermatogonia before birth
What happens to spermatogonia before birth?
Puberty in spermatogenesis
What happens at puberty in spermatogenesis?
Spermatogenesis after puberty
What happens after puberty in spermatogenesis?
Structure of spermatozoa
Describe the structure of spermatozoa.
Oogenesis location and origins
Where does oogenesis occur and what are oogonia?
Oocytes before birth
What happens to oocytes before birth?
Puberty in oogenesis
What happens at puberty in oogenesis?
Oogenesis after puberty
What happens after puberty in oogenesis?
Menopause
What is menopause?
Functional ova from primary oocyte
How many functional ova are produced from one primary oocyte?
Stages of labour
What are the three stages of labour?
Stage 1 (Dilation)
What happens in Stage 1 (Dilation)?
Breaking of waters
What is 'breaking of waters'?
Stage 2 (Expulsion)
What happens in Stage 2 (Expulsion)?
Stage 3 (Delivery of placenta)
What happens in Stage 3 (Delivery of placenta)?
After fertilisation
What happens after fertilisation?
Three germ layers
Name the three germ layers and give examples.
Embryonic membranes
What are the embryonic membranes and their function?
Placenta and umbilical cord
What role does the placenta and umbilical cord play in circulation?
Role of progesterone in pregnancy
What is the role of progesterone in pregnancy?