Respiratory:
* Stasis of mucus increases risk for infection
* Early manifestations: wheezing, rhonchi, dry, non-productive cough
* Increased involvement: dyspnea, paroxysmal cough, obstructive emphysema and atelectasis on chest x-ray
* Advanced involvement: cyanosis, barrel-shaped chest, clubbing of fingers and toes, multiple episodes of bronchitis or bronchopneumonia
Gastrointestinal:
* Large, frothy, bulky, greasy, foul-smelling stools
* Failure to gain weight or weight loss
* Delayed growth patterns
* Distended abdomen & thin arms and legs (infant)
* Reflux
* Prolapse of rectum (infant & child)
Integumentary:
* Sweat, tears, and saliva have excessively high content of sodium & chloride
Endocrine & Reproductive:
* Viscous cervical mucus, decreased or absent sperm, decreased insulin production