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Vocabulary-style flashcards covering key terms and definitions from the respiratory system lecture notes.
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Primary functions of the respiratory system
Exchange gases (O2 and CO2), produce vocal sounds, sense of smell, and regulate blood pH.
External respiration
Gas exchange between air in the lungs and blood (air → blood).
Internal respiration
Gas exchange between blood and body tissues (blood → tissues).
Respiration
Process of gas exchange between the atmosphere, lungs, and tissues.
Cellular respiration
Cells use oxygen and sugars to produce energy (ATP).
Mitochondrion
Organelle where cellular respiration occurs to generate ATP.
Upper respiratory tract
Nose, nasal cavity, sinuses, and pharynx.
Lower respiratory tract
Larynx, trachea, bronchial tubes, and lungs.
Nose
External structure with nostrils; supported by bones and cartilage; filters large particles.
Nasal cavity
Hollow space behind the nose where air is warmed and moistened.
Nasal septum
Bone that divides the nose into left and right sides.
Nasal concha
Bones (superior, middle, inferior) that divide the nasal cavity and increase surface area.
Mucus membrane
Warm and moisten air; traps particles like dust.
Deviated septum
Septum bends to one side, causing a crooked nose; sometimes repaired surgically.
Paranasal sinuses
Air-filled spaces (maxillary, frontal, ethmoid, sphenoid) that reduce skull weight and voice resonance.
Pharynx
Space behind the oral cavity between the nasal cavity and larynx; includes nasopharynx, oropharynx, laryngopharynx.
Larynx
Enlargement at the top of the trachea that houses vocal cords and contains cartilage.
Thyroid cartilage
Adam’s apple; a main laryngeal cartilage.
Cricoid cartilage
Ring-shaped cartilage of the larynx.
Epiglottic cartilage
Cartilage supporting the epiglottis that prevents food from entering the airway.
False vocal folds
Help close the airway during swallowing; do not produce sound.
True vocal folds
Produce sound; tension changes pitch.
Glottis
Triangular slit between vocal cords; opens for breathing and talking.
Epiglottis
Flap that closes the airway during swallowing to prevent food from entering the trachea.
Trachea
Windpipe; reinforced by cartilage rings; leads to the bronchial tree.
Primary bronchi
Main airways branching from the trachea into each lung.
Secondary (lobar) bronchi
Bronchi that service each lobe of the lungs.
Tertiary (segmental) bronchi
Bronchi that service bronchopulmonary segments.
Bronchioles
Small airways leading to the alveolar ducts and sacs.
Alveoli
Tiny air sacs where gas exchange occurs; connected to capillaries.
Alveolar ducts
Tubes that connect bronchioles to alveolar sacs.
Alveolar sacs
Clusters of alveoli where gas exchange occurs.
Pleura
Two-layered membrane encasing the lungs: visceral and parietal pleura.
Pleural cavity
Space between pleurae containing pleural fluid.
Pulmonary ventilation
Breathing; depends on atmospheric, intra-alveolar, and intrapleural pressures.
Atmospheric pressure
Pressure exerted by the air around us; at sea level 760 mm Hg.
Intra-alveolar (intrapulmonary) pressure
Air pressure inside the alveoli; fluctuates with breathing and equals atmospheric pressure during normal breathing.
Intrapleural pressure
Pressure inside the pleural cavity; normally negative relative to intra-alveolar pressure.
Transpulmonary pressure
Difference between intrapleural and intra-alveolar pressures; determines lung size.
Boyle’s law
At constant temperature, pressure and volume are inversely related: P1V1 = P2V2.
Tidal volume (TV)
Air normally inhaled or exhaled during quiet breathing (~500 mL).
Expiratory reserve volume (ERV)
Extra air that can be exhaled beyond a normal tidal expiration.
Inspiratory reserve volume (IRV)
Extra air that can be inhaled beyond a normal tidal inspiration.
Residual volume (RV)
Air remaining in the lungs after maximal exhale; prevents collapse of alveoli.
Total lung capacity (TLC)
Sum of all lung volumes; total amount of air the lungs can hold.
Vital capacity (VC)
Amount of air that can be moved in and out; sum of TV, IRV, and ERV (excluding RV).
Functional residual capacity (FRC)
Volume remaining after a normal tidal expiration (ERV + RV).
Spirometry
Tests that measure lung volumes and air flow (e.g., FVC, FEV, PEF).
Forced vital capacity (FVC)
Volume of air exhaled after a maximum inhalation.
Ventilatory measures (FEV, FEF 25-75)
FEV: volume exhaled in a specific time; FEF 25–75%: mid-expiratory flow rate.
Respiratory center
Brainstem groups (medulla and pons) that regulate inspiration and expiration.
Dorsal respiratory group (DRG)
Medullary group primarily involved in inspiration.
Ventral respiratory group (VRG)
Medullary group involved in forced expiration and inspiration.
Pneumotaxic area
Pontine center that inhibits inspiration to regulate breathing rate.
Apneustic center
Pontine center that promotes inspiration.
Hyperventilation
Increased breathing rate/depth causing CO2 loss and respiratory alkalosis.
Respiratory membrane
Thin barrier where gas exchange occurs; consists of alveolar and capillary walls.
Hypoxia
Lack of sufficient oxygen in body tissues.
Asphyxia
Severely diminished oxygen supply due to inability to breathe normally (e.g., choking).
Pneumothorax
Collapsed lung due to air in the pleural space.
Pleural effusion
Fluid accumulation in the pleural space.
Cystic fibrosis
Hereditary disease with thick mucus in lungs causing breathing difficulty.
Chronic obstructive pulmonary disease (COPD)
Obstruction of airways, typically due to chronic bronchitis and/or emphysema.
Asthma
Inflammation with bronchospasm and mucus production; bronchial hyperreactivity.
Bronchitis
Inflammation of the airways with mucus production; can be acute or chronic.
Emphysema
Alveolar damage with enlarged air spaces and reduced surface area for gas exchange.
Pneumonia
Infection causing alveoli to fill with fluid or pus.
Tuberculosis
Infectious disease caused by Mycobacterium tuberculosis affecting the lungs.
Influenza
Viral respiratory infection affecting the nose, throat, and lungs.
Rhinovirus
Common cold virus that infects the upper respiratory tract.
Pertussis (Whooping cough)
Bacterial infection causing severe coughing and gasping for breath.
Sleep apnea
Pause or slowing of breathing during sleep.