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What are the functions of the urinary system?
excretion of waste products from bodily fluids
elimination of waste
homeostatic regulation of volume and concentration of blood plasma
what are the essential homeostatic funtions?
regulating blood volume and pressure by adjusting volume of water lost in urine through the use of hormones EPO and Renin
regulating plasma concentrations of Na, K, Cl, and other ions
helps to stabilize blood pH, controls loss of H ions and bicarbonate ions in urine
conserves valuable nutrients, prevents their excretion in urine
assists the liver by detoxifying poisons and deaminating amino acids
what do the kidneys do?
produce urine
where are the adrenal glands located?
on top of the kidneys
what is the urinary tract made of?
2 ureters
urinary bladder
urethra
what do the ureters do?
transport urine from kidneys to bladder
what does the bladder do?
stores urine temporarily
what does the urethra do?
transports urine from the bladder to outside the body
what does the renal fascia do?
anchors kidney to surrounding structures, outer most structure
what is the adipose capsule?
adipose tissue that surround the kidneys
what is the renal capsule?
covers the outer surface of the kidney
what is the hilum?
point of entry for artery, nerve, and exit for vein and ureters
what is the renal sinus?
an internal cavity inside of the kidney
what is the renal cortex?
the outer portion of the kidney
what is the renal medulla?
the inner portion of the kidney
what are the renal pyramids?
6-18 triangle shaped structures in the medulla
what is the renal papilla?
tip or point of pyramids, projects into renal sinus
what are the renal columns?
bands of tissue in between the pyramids
what does the minor calyx do?
collects urine from the papilla
what does the major calyx do?
collects urine from 4 to 5 minor calyx
what are nephrons?
functional unit of the kidneys
what is the order of renal blood flow?
Renal artery → Segmental arteries → Interlobar arteries → Arcuate arteries → Interlobular arteries → Afferent arterioles → Glomerulus → Efferent arteriole → Peritubular capillaries* → Interlobular veins → Arcuate veins → Interlobar veins → Renal vein
what do renal nerves do?
adjusts the rate if urine formation by altering blood flow and pressure at nephron
stimulates renin which stimulates water and salt reabsorption at nephron
what are cortical nephrons?
located totally in the superficial cortex of the kidney
what are juxtamedullary nephrons?
have long loops of henale that extend deep into the medulla, produce concentrated urine
what is the vasa recta?
long capillaries that parallel loop of henle in juxtamedullary nephrons
bowman’s capsule
cup-shaped outer wall of renal corpuscle (parietal epithelium)
capsular space
space between parietal and visceral epithelium
glomerulus
interconnected capillaries inside the renal corpuscle (visceral epithelium)
afferent arteriole
blood into the glomerulus
efferent arteriole
blood out of the glomerulus
podocytes
(cells in visceral epithelium) – contain feet known as Pedicels
filtration slits
gaps between pedicels
proximal convoluted tubule (PCT)
First segment of the renal tubule
tubular fluid- fluid inside renal tubule
peritubular fluid- interstitial fluid surrounding renal tubule
Reabsorption of nutrients, ions, water & plasma proteins is the primary function of PCT
loop of henle
Descending limb connects to PCT
Ascending limb connects to DCT
Thick segment- refers to size of cells not the diameter of lumen, pumps sodium & chloride ions out of fluid
Thin segment- freely permeable to water
distal convoluted tubule (DCT)
Passes between afferent and efferent arterioles
Active secretions of ions, acids, drugs and toxins
Selective reabsorption of Na ions, Ca ions, & water
juxtaglomerular apparatus
secretes hormones EPO and Renin
macula densa
cluster if cells along DCT
juxaglomerular cells
smooth muscle fibers
collecting duct
Transports tubular fluid from nephron to renal pelvis
Adjusts the final composition, concentration, and volume of urine
Several collecting ducts unite to form a papillary duct
PAPILLARY DUCT → MINOR CALYX → MAJOR CALYX
purpose of organic waste products
produce urine to regulate volume and composition of blood
urea
most abundant organic waste, most of it from breaking down amino acids, 21 g/day
creatinine
generated in skeletal muscle from the break down of creatine phosphate, 1.8g/day, all is excreted
uric acid
formed from recycling nitrogenous bases RNA, 480mg/day
filtration
blood pressure forces water & solutes across wall of the glomerulus
reabsorption
removal of water & solutes from the filtrate, occurs after filtrate has left the renal corpuscle
secretion
transport of solutes into renal tubules, back up process to filtration in order to remove all undesirable materials from blood plasma