Amino Acids Groups

Glycine

Gly, G

nonpolar, aliphatic

Alanine

Ala, A

nonpolar, aliphatic

Proline

Pro, P

nonpolar, aliphatic

Methionine

Met, M

nonpolar, aliphatic

Valine

Val, V

nonpolar, aliphatic

Leucine

Leu, L

nonpolar, aliphatic

Isoleucine

Ile, I

nonpolar, aliphatic

Phenylalanine

Phe, F

nonpolar, aromatic

Tryptophan

Trp, W
pKa = -2.4

nonpolar, aromatic

Serine

Ser, S

polar, uncharged

Threonine

Thr, T

polar, uncharged

Cysteine

Cys, C
pKa = 8.35

polar, uncharged

Asparagine

Asn, N

polar, uncharged

Glutamine

Gln, Q

polar, uncharged

Tyrosine

Tyr, Y
pKa = 10.07

nonpolar, aromatic

Aspartate

Asp, D
pKa = 3.86

negatively charged

Glutamate

Glu, E
pKa = 4.25

negatively charged

Lysine

Lys, K
pKa = 10.79

positively charged base

Arginine

Arg, R
pKa = 12.48

positively charged base

Histidine

His, H
pKa = 6.04

positively charged

How many nonpolar, aliphatic amino acids are there? What are they?

7

• G (Glycine, Gly)

• A (Alanine, Ala)

• V (Valine, Val)

• L (Leucine, Leu)

• I (Isoleucine, Ile)

• P (Proline, Pro)

• M (Methionine, Met)

How many aromatic amino acids are there? What are they?

3

• F (Phenylalanine, Phe)

• Y (Tyrosine, Tyr)

• W (Tryptophan, Trp)

How many polar, uncharged amino acids are there? What are they?

5

• N (Aspargine, Asn)

• Q (Glutamine, Gln)

• S (Serine, Ser)

• T (Threonine, Thr)

• C (Cysteine, Cys)

How many positively charged amino acids are there?

3

• H (Histidine, His)

• K (Lyseine, Lys)

• R (Arginine, Arg)

How many negatively charged amino acids are there?

2

• D (Aspartate, Asp)

• E (Glutamate, Glu)

what is the pKa of aliphatic amines?

10

what is the pKa of carboxylic acids?

5

What is the pKa of phenol?

10

What is pKa of sulfonic acid?

1

What is the pKa of aromatic amines?

5