Sn2 Reactions.

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10 Terms

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General reaction

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2
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What is a nucleophile?

a “nucleus loving” molecule; donates an electron pair to form a bond.

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List the common nucleophiles

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<p>Sn2 Mechanism. How many steps? Rate equation?</p>

Sn2 Mechanism. How many steps? Rate equation?

Single step with no intermediates. Bimolecular.

<p>Single step with no intermediates. Bimolecular.</p>
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Describe the stereochemistry of SN2 Reactions

Inversion of configuration at the chiral center.

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What substrates can undergo Sn2 Reactions?

methyl, primary, and secondary substrates.

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How many steps are in a Sn2 reaction? What are they?

2 Steps. Step 1 - Fast protonation. Step 2 - Slow nucleophilic attack.

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What is a nucleophilic attack?

The nucleophile approaches the substrate (typically an alkyl halide) from the opposite side of the leaving group.

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