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what is a genetic variant/mutation?
a change in the bases of a gene
how can mutations occur?
when DNA is not copied properly during cell division
what external factors can cause mutations?
environmental factors, such as radiation
can mutations affect an organisms phenotype?
yes
what are alleles?
different forms of a gene
what determines an individual’s characteristics?
the alleles they inherit
how can a mutation in the non coding region affect transcription?
it may prevent RNA polymerase from binding properly, reducing transcription
other mutations can result in the enzyme binding to the non coding region better and producing more mRNA