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what connects the hypothalamus to the pituitary
infundibulum
the pituitary controls the hormone release of which organs and glands
thyroid, adrenal, gonads, and liver
what are the two sections of the pituitary
adenohypophysis (anterior) and neurohypophysis (posterior)
how are pituitary hormones produced
by neurons in the hypothalamus
what is a portal system
when two capillary beds are interconnected
explain the process of anterior pituitary hormone production and secretion
-hormones (from hypothalamus) bind to receptors in the anterior pituitary
-they signal to either stimulate or inhibit the secretion of pituitary hormones
-pituitary hormones are released into the portal vessels
-the hormones travel from the portal vessels into general circulation
what is the process for posterior pituitary hormone production and secretion
-hypothalamic neurons send their axons into the posterior pituitary
-pituitary releases hormones into capillary beds
-hormones travel from capillary beds into general circulation
what hormones are produced by the anterior pituitary
-adenocorticotropic hormone
-thyroid stimulating hormone
-growth hormone
-prolactin (milk production)
-luteinizing hormone
-follicle stimulating hormone
-melanocyte stimulating hormone
what hormones are released from the posterior pituitary
-anti-diuretic hormone
-oxytocin
what does TSH stimulate the release of
thryroxine (T4) and triiodothyronine (T3)
what stimulates the release of TSH
thyrotropin releasing hormone (TRH)
where is ADH
the kidneys
what does ADH do
-increases water retention in the kidneys resulting in lower volumes of urin
-increases thirst
what stimulus triggers the release of ADH
-an increase in blood osmolarity (solutes in the blood)
or
-decrease in blood pressure
what does ethyl alcohol do
-inhibits release of ADH
-causes diuresis (lots of peeing)
-decreased water retention
what does oxytocin do
-causes contraction of myoepithelial cells for milk ejection during nursing
-causes uterine myometrial contractions during labor
what can cause the release of oxytocin
mechanical stimulation of the vagina, cervix, or uterus (which would induce a fetal ejection reflex)
what is the purpose of synthetic oxytocin
used to induce labor and reduce postpartum bleeding following the delivery of the placenta
what does prolactin do
-stimulates mammary gland development and milk production
-inhibits ovulation and shortens luteal phase in ovarian cycle
what inhibits prolactin
dopamine
what does estrogen do in terms of prolactin
it stimulates prolactin secretion and synthesis in the pituitary
what happens during pregnancy in terms of prolactin
is it released more and more during pregnancy and hits it max levels at term
what is the stimulus of prolactin most potent
during nursing
is blood glucose relatively constant
yes
what is the range for blood glucose
60-120 mg/dL
when does insulin rise
in response to food intake (after eating a meal)
do glucagon levels remain relatively stable
yes
what is glucagon
-counteracts the actions of insulin
-stimulates glucose production to increase blood glucose levels
what is the source of blood glucose after a meal
carbohydrates for 2-3 hours after the meal
what does glucagon stimulate between meals
glycogenolysis in the liver
what is glycogenolysis
breakdown of glycogen into glucose for quick energy
what happens when hepatic (liver) glycogen is low
glucagon and cortisol stimulate gluconeogenesis
what is gluconeogenesis
the creation of new glucose
what is the order of the postabsorptive state
1.carbs are source for blood glucose 2-3 hours after meal
2.glycogenesis occurs between meals (glycogen in liver breaks down into glucose)
3.when hepatic glucose is low gluconeogenesis occurs