Glycogen synthesis

Step 1 of glycogen synthesis

Uptake of glucose and phosphorylation

Step 1 synthesis breakdown

Glucose transporters sense and take glucose from the blood and transport to the cytosol

Then phosrylated

What enzyme phosphorylation the glucose in step 1

Hexokinase turns it into glucose-6-phosphate

Step 2 of glycogen synthesis

isomerization of glucose-6-phosphate to glucose-1-phosphate

Step 2 pf synthesis described

Is done by the enzyme of phosphoglucomutase

Step 3 of glycogen synthesis

The formation of UDP-glucose

Step 3 glycogen synthesis breakdown

Has two separate steps:

1. transfer of UMP to Glucose-1-Phosphate causes the release of PPi and UDP

2. PPi breaking and releasing energy

Step 4 of glycogen synthesis

glycogen chain elongation

Step 4 of glycogen synthesis described

Needs a primer (Glycogenin) and will attach to a glucose molecule

• take glucose from the UDP-glucose

• glucose will attach from the (1,4) positio

Step 5 of glycogen synthesis

Branching enzyme action

Step 5 of glycogen synthesis

to increase the solubility, glycogen branching enzyme will add 7 blocks glucose to an interior site to produce a new aplha(1→6) glycosidic bond called a branch point