M2 ass intv. pharma

RCIS

70-100 U/Kg

What is the dose for heparin in the cath lab?

ACT: 250-350 seconds

repeat every 20-30minutes

What is the ACT goal for heparin use during a PCI? How often should an ACT be performed?

reverse with Protamine Sulfate

1 mg/100 U Heparin or

approx 25 mg slow IV injection over 10 minutes

What is the reversal agent for heparin?

Heparin-Induced Thrombocytopenia

Immune cell mediated thrombocytopenia that can lead to thrombosis, stroke, loss of limb, or other ischemic events.

What is HIT and why is it dangerous?

for femoral procedures warfarin is held for several days to obtain a preprocedure INR of less than 1.8.

transradial procedures can often be safely performed regardless of the INR. (international normalized ratio)

How long should warfarin be held prior to a cardiac cath?

decrease platelet aggregation and inhibit thrombus formation

Aspirin acetylate irreversibly binds and inactivates platelet cyclooxygenase, inhibiting production of thromboxane A2 (TXA2), which is a potent inducer of platelet aggregation and vasoconstriction via the production of cyclic adenosine monophosphate

How do antiplatelet agents prevent thrombus formation?

Cangrelor

2-3 min

Which antiplatelet agent has the quickest platelet recovery time?

may be helpful in a patient with recent subacute stent thrombosis

What is platelet function testing and what is it used for?

arterial and venous vasodilator, multiple uses

relieve coronary spasm,

relieves angina and heart failure by causing coronary dilation

reducing preload and afterload

How is nitroglycerin used in the cath lab?

improving distal perfusion

SVT and radial artery access

What is verapamil used to treat?