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Nicotine
Enters the lungs on tiny particles called tar. Rapidly absorbed in the lungs.
nicotinic cholinergic receptors (NaCH)
Nicotine actives…?
nicotinic cholinergic receptors (NaCH)
ionotropic receptors which produce rapid excitatory responses and let in Na+
acetylcholine
Which neurotransmitter are nicotinic cholinergic receptors associated with?
decrease
Does nicotine increase and decrease appetite?
Bupropion and Varenicline
What are treatments for nicotine addiction?
Bupropion
A DA and NE reuptake inhibitor and a weak NaCH antagonist
Varenicline
A partial agonist at high-affinity NaCH