Negative selection and self-tolerance revisited

0.0(0)
studied byStudied by 0 people
learnLearn
examPractice Test
spaced repetitionSpaced Repetition
heart puzzleMatch
flashcardsFlashcards
Card Sorting

1/3

encourage image

There's no tags or description

Looks like no tags are added yet.

Study Analytics
Name
Mastery
Learn
Test
Matching
Spaced

No study sessions yet.

4 Terms

1
New cards

How does central tolerance work?

removes self-reactive T and B cells through apoptosis during negative selection.

2
New cards

What mechanisms are involved in peripheral tolerance?

involves regulatory T cells and the need for helper T cells to activate B cells.

3
New cards

What happens to T and B cells that don't receive a costimulatory signal?

They become anergic, meaning they are inactivated and do not respond.

4
New cards

-

-