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Digestive process
a multistep process of breaking down foods into absorbable components using mechanical and chemical means in the gastrointestinal (GI) tract
lumen
interior of the intestinal tract
Gastrointestinal tract consists of:
– Mouth
– Esophagus
– Stomach
– Small and large intestines
– Accessory organs: pancreas, liver, gallbladder
-rectum
What are the accessory organs
pancreas, liver, gallbladder
Mechanical digestion
chewing, grinding food, and moving it through the GI trac
Chemical digestion
digestive juices and enzymes break down food into absorbable nutrients
Segmentation
(sloshing) mixes chyme with chemical secretions; increases time food comes into contact with intestinal walls
Pendular movement
(constrictive wave) enhances
nutrient absorption in small intestine
bolus
mixture of food and digestive secretions

Peristalsis
the forward, rhythmic motion that helps mix
food with digestive secretions and propels the mixture,
called a bolus, from the esophagus through the large
intestine. It is a form of mechanical digestion.
peristalsis is a form of what kind of digestion
mechanical
Chyme
semi-liquid food mass
Main roles of the GI tract are to
– Break down food into smallest components
– Absorb nutrients
– Prevent microorganisms or other harmful compounds
in food from entering tissues of the body
– Maintain the gut microbiome
you swallow what after chewing?
bolus
Mouth (GI woman)
ingestion: food enters the GI tract through the mouth
Mechanical Digestion: chewing tears and shreds food and mixes it with saliva, forming bolus
Chemical Digestion: carbohydrate enzymes secreted by the salivary glands begin carbohydrate breakdown
Pharynx and esophagus (GI woman)
propulsion: swallowing and peristalsis move the bolus from mouth to stomach
Stomach (GI woman)
mechanical digestion: movements mix and churn the bolus with acid enzymes and gastric fluid to form chyme
chemical digestion: stomach enzymes begin the digestion of proteins
absorption: a few fat soluble substances are absorbed through the stomach wall
Both mechanical and chemical digestion begin in the
mouth
Saliva
contains water, electrolytes, mucus, and a few enzymes
what is the job of saliva
Softens, lubricates, dissolves food particles
Bolus
food mass) moves into pharynx, is swallowed,
and enters the esophagus
Epiglottis
closes off trachea during swallowing to
prevent food from lodging in the windpipe and lungs
Once swallowed, a bolus is pushed down your
esophagus by
peristalsis into the stomach
Gastroesophageal sphincter (lower esophageal
sphincter (LES))
bottom of esophagus narrows and
relaxes to allow food into stomach
The gastroesophageal sphincter then closes to prevent
backflow of
hydrochloric acid (HCl) from stomach
Gastroesophageal reflux disease (GERD) is
“reflux"
of stomach acid that causes "heartburn" (irritation of
esophagus lining)
what is the name of the lipoprotein that transports soluble nutrients from the small intestine
chyloproteins
carbohydrates are primarily found in?
plant-based foods
Glucose is the most abundant
carbohydrate in nature
Glucose (chem)
C6H12O6
monosaccharides
contain one sugar
disaccharides
two sugars
The stomach is a muscular organ that continues
mechanical digestions by
churning and contracting to mix
food with digestive juices for several hours
Stomach produces powerful digestive secretions such as
HCl which activates enzyme pepsin, enhances absorption of minerals, and destroys some ingested microorganisms
Gastrin
Pepsin is secreted by
the stomach
what is gastrin (found in the stomach)
hormone stimulates digestive activities and
increases gastric motility and emptying
Pyloric sphincter
located between the stomach and small intestine; allows about 1 teaspoon of chyme to enter the small intestine every 30 seconds
– Prevents backflow of intestinal contents
Small intestine (three segments)
long, narrow, coiled
▪ Duodenum (shortest segment)
▪ Jejunum
▪ Ileum (longest segment)
small intestine accounts for about _______ of the GI tract
20 feet
The small intestine increases surface area by
villi (finger like)
microvilli (hair like)
circular folds
Ileocecal sphincter
prevents backflow of fecal matter into ileum as chyme enters the large intestine
where is majority of the nutrients absorbed? (mainly water and electrolytes)
large intestine
the large intestine has how many sections?
3:
cecum
colon
rectum
how big is the large intestine
5 feet long, 2.5 inches in diameter
Larrge intestine is also known as
the colon
what is stored in the rectum?
stool or feces
Anus (anal sphincter)
connected to the rectum and controlled by two sphincters: internal and external
what is the largest internal organ of the body where BILE is produced
the liver
bile is needed for what?
fat digestion
Gallbladder stores what
stores bile
Gastrin stimulates stomach to release
HCl and enzyme gastric lipase
What stimulates hunger
ghrelin
Secretin causes
pancreas to release bicarbonate to
neutralize HCl
Cholecystokinin stimulates
pancreas to secrete
digestive enzymes, controls pace of digestion
Amylase
digests carbohydrate
Lipase
digests fats
Trypsin, chymotrypsin, and carboxypeptidase
digests protein
bile helps digest what
fat
Bile is recycled back to the liver from the large intestine through
enterohepatic (entero =intestine, hapatic = liver) circulation