RX523 Volume of Distribution Principles

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Last updated 10:54 PM on 9/13/26
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4 Terms

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Volume of distribution

An indicator of the extent of drug distribution into the body fluids and tissues

2
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What does a higher apparent Vd mean?

Greater extent of drug distribution

3
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What does a smaller Vd indicate?

- Higher Cp

- Higher water solubility

- Increased plasma protein binding

- Decreased tissue binding

4
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What does a larger Vd mean?

- Smaller Cp

- Higher lipid solubility

- Decreased plasma protein binding

- Increased tissue binding