Immunization Module Quiz Answers-Pharmacy Practice II (Added all CE Impact Questions)

Which of the following antibody classes is the mediator of allergy and anaphylaxis?

IgE

Which of the following describes the role of helper T cells in mounting an immune response to a vaccine?

Produce cytokines that stimulate B cells to produce antibodies

Which of the following is an advantage of passive immunity compared to active immunity?

Passive immunity protects almost immediately

Two people we do not give live-attenuated Vaccines

Immunocompromised & Pregnant

Which of the following is an example of passive immunity?

Administration of high titer immune globulin

Which of the following is/are true regarding live attenuated vaccines?

More than one live attenuated vaccine can be given at the same visit

Which of the following represents a true contraindication to measles vaccine?

Vaccine Candidate is Pregnant

Which of the following is a contraindication to receiving live vaccines?

Taking prednisone 40 mg by mouth daily for 21 days

In general, increasing the interval between doses of a multi-dose vaccine diminishes the effectiveness of the vaccine.

False

Which of the following vaccines is contraindicated for a pregnant woman?

Live attenuated influenza vaccine (LAIV)

What is the threshold dose of prednisone at which a patient is considered immunosuppressed?

20 mg per day for 14 days or longer

For how long after completing chemotherapy or radiation must a person wait before receiving a live vaccine?

At least three months

Live attenuated vaccines are contraindicated in patients who are pregnant.

True

If a patient has a history of contact dermatitis from neomycin, they cannot receive vaccines that contain neomycin.

False

Precaution or Contraindication: Anaphylaxis to a dose of vaccine and a subsequent dose of that vaccine

Contraindication

Precaution or Contraindication: Moderate acute illness without fever and any vaccine

Precaution

Precaution or Contraindication: Severe immunosuppression and live attenuated vaccines

Contraindication

Precaution or Contraindication: History of intussusception and rotavirus vaccine

Contraindication

Precaution or Contraindication: Family history of seizures and MMRV Vaccine

Precaution

Pain, Swelling, Redness at injection site

Local Adverse Events

Headache & Fever

Systemic Adverse Events

Anaphylaxis

allergic reaction

Boosters are usually not necessary for live attenuated vaccines.

True

In general, the first dose of an inactivated vaccine usually provides protection.

False

What is the correct interval between two live vaccines if they are not simultaneously administered?

At least 4 weeks

Which combination of vaccines can be administered at the same visit?

Fluzone and Shingrix

In general, giving two or more vaccines on the same day (simultaneous administration) of all recommended vaccines is appropriate.

True

Increasing the interval between doses of a multidose vaccine does not diminish the effectiveness of the vaccine.

True

Decreasing the interval between doses of a multidose vaccine does not diminish the effectiveness of the vaccine.

False

Refrigerator and freezer temperature logs must be kept for a period of at least:

3 years

The liquid diluent for recombinant zoster vaccine (RZV) is:

ASO1B Adjuvant Suspension

Which of the following describe appropriate storage conditions for inactivated vaccines?

Should be stored in the center of the refrigerator

Which of the following vaccines must be stored in the freezer?

Varicella vaccine

Which of the following is an advantage of immunization in nontraditional settings, such as a pharmacy?

Increased access and convenience for the patient

Which of the following describes the benefits of using standing orders for immunization?

Increases immunization coverage among adults in a variety of practice settings

Which of the following is true regarding best practices for vaccine preparation?

Syringes other than those filled by the manufacturer should be administered immediately

Refrigerator and freezer temperature(s):

Must be maintained between +35 and +46 F and -58 and +5 F respectively

Which of the following can be done to prevent vaccine storage problems?

Place containers of water labeled "do not drink" into refrigerator to stabilize temperatures

If the date on the label of a vaccine or diluent has a specific month and year, the vaccine can be used only until the first day of the month listed.

False

The primary vaccine coordinator at a practice site should be responsible for: (select all that apply)

Ensure that staff is adequately trained AND ensuring that vaccines are stored and handled correctly

Which of the following is true regarding Vaccine Information Statements (VIS)?

They are designed to provide information about vaccines, or, in the case of a minor, the child's parent or guardian about the risks and benefits of each vaccine

Which of the following is the appropriate strategy for giving the Vaccine Information Statement (VIS) to patients?

The VIS should be given to the patient prior to immunization so the patient has time to review it and ask questions

Which of the following items should be included in immunization records for vaccines administered in the pharmacy?

Type of vaccine, date administered, site of administration, vaccine manufacturer and lot number, VIS publication date with the date given to the patient/parent or guardian, and the initials and title of the practitioner administering the vaccine

Which of the following best describes immunization information systems (IISs)?

The value of the IIS is that it allows healthcare providers to access immunization records to facilitate clinical decision making

The recommendations for prevention of vaccine preventable diseases made by the Advisory Committee on Immunization Practices (ACIP) are published in which of the following?

Morbidity and Mortality Weekly Report (MMWR)

Which of the following most accurately describes the federally-mandated training for employees with blood and body fluid exposure?

Initial training and annual retraining are required for bloodborne pathogens

Which of the following is true regarding bloodborne pathogen exposure and immunizations?

Every pharmacy providing immunizations must have a bloodborne pathogen exposure control plan

Which of the following should be completed in all pharmacies that provide immunizations?

Training employees about bloodborne pathogens and the pharmacy's bloodborne exposure control plan

How should the disposal of sharps containers be handled?

Arranged with the local waste management company

Why is the safety of vaccines held to a higher standard than for most medications?

They are administered to healthy people to prevent disease rather than to sick people to cure disease

The Countermeasures Injury Compensation Program (CICP):

Provides benefits to seriously injured individuals that resulted from using certain antivirals

Which of the following scenarios are healthcare professionals encouraged to use Vaccine Adverse Event Reporting System (VAERS) for reporting?

Any clinical significant adverse event after vaccination

Which of the following is specifically listed as a VAERS reportable event for measles vaccine?

Thrombocytopenic purpura

Which of the following describes the Vaccine Injury Compensation Program?

Protects the immunization provider and vaccine manufacturer from personal liability

Which of the following is specifically listed as a VAERS reportable event for tetanus vaccine?

Brachial neuritis

One of the Clinical Immunization Safety Assessment (CISA) project's main goal is to serve as a vaccine safety resource for consultation on clinical vaccine safety issues.

True

Which of the following is a valid contraindication to vaccination?

Anaphylaxis after a previous dose or vaccine component

Which manifestation of anaphylaxis is epinephrine used to treat?

Hypotension

Anaphylaxis generally will not occur until 1-2 hours after administration of a vaccine.

False

Which of the following is the reason that a second dose of measles vaccine is recommended for all college study?

the second dose provides another opportunity for seroconversion for those failure to respond to the first dose

Which of the following patients is a candidate for varicella vaccine?

5-year-old who received DTaP four weeks ago

Which of the following is a contraindication to receipt of the rotavirus vaccine?

History of intussusception

Which of the following patients is the best candidate for hepatitis A vaccine?

A 15-month-old male also receiving a 3rd dose of hepatitis B vaccine

Which of the following patients is a candidate for recombinant zoster vaccine (RZV)?

A 62-year-old female with autoimmune hepatitis controlled with prednisone 30 mg daily

A 48-year-old male recently diagnosed with cancer who will start chemotherapy in two weeks

A 78-year-old female receiving anti-rejection drugs for a kidney transplant two years ago

A 68-year-old male with COPD treated with inhaled fluticasone/salmeterol

Which of the following is true regarding the use of Haemophilus influenzae type b vaccine?

Is a polysaccharide vaccine conjugated to a protein to improve immunogenicity in infants

For which of the following patients is the human papillomavirus vaccine series indicated?

A 16-year-old female who recently became sexually active

Which of the following individuals has a risk factor for poor response to the hepatitis B vaccine series?

A 66-year-old male who is in renal failure and waiting for a cadaveric kidney transplant

Which of the following describes a limitation of the quadrivalent meningococcal conjugate vaccine?

No protection from serogroup B

For which of the following individuals is a mumps vaccine recommended?

A 22-year-old female who received a single dose of MMR and just accepted a position as a nurse on a general surgery unit

Which of the following is a meningococcal serogroup B vaccine?

Bexsero

Which is true about the incidence of measles in the United States?

A majority of cases are a result of importation in unvaccinated populations

Sam is a 48-year-old healthy male presenting to a pharmacy wondering if he would be able to get the recombinant zoster vaccine (RZV). You explain the guidelines to Sam; which explanation is correct?

RZV is effective in reducing the incidence of shingles and is indicated in immunocompetent patients aged 50 and older.

Rotavirus is a common childhood illness accounting for 1/3 of hospitalizations due to diarrhea. What is the appropriate vaccine recommendation for a 2-month-old child with a known history of latex allergy?

Rotateq at age 2, 4, and 6 months

A mother is considering HPV vaccination for her young son, but some commercials that she recalls lead her to believe this vaccine is for prevention of cervical cancer, and does not see how this will benefit her son. How do you explain to this mother the importance of this vaccine for her son?

There are benefits for protection for him contracting strains of virus as well as spreading the virus to others

This is the most common sexually transmitted infection

Yes, this does prevent cervical, vulvar, and vaginal cancer in women; however, it also protects against genital warts, anal cancer, as well as other cancer strains in men

Hepatitis B is a virus spread by parenteral routes including blood transfusions, sharing of needles, sexual contact, and mother to neonate. Which is true about hepatitis B?

Using needles which are not long enough will decrease response rates to the vaccine

Patients with diabetes are at an increased risk of hepatitis B due to sharing of diabetes supplies including blood glucose meters

Death commonly occurs as a result of cirrhosis and hepatocellular carcinoma

Renal failure will decrease response to hepatitis B vaccine

For which of the following individuals is inactivated influenza vaccine (IIV) NOT recommended?

A 2-month-old healthy infant

Which of the following is an appropriate response to a patient who tells you that she is concerned that she will get influenza from the inactivated influenza vaccine (IIV)?

Other than a higher incidence of sore arm, influenza vaccine has a side effect profile similar to placebo

For which of the following individuals would it be acceptable to use live attenuated influenza vaccine?

A 48-year-old healthy mechanical engineer whose spouse has type 2 diabetes

Which of the following is the appropriate timing for influenza vaccine administration?

Influenza vaccine should be administered no sooner than September or October and should continue throughout the season

Which of the following is a likely benefit of annual influenza immunization of school-aged children?

Decreases the magnitudes of influenza epidemics in the community

Which of the following is the appropriate schedule for polio immunization in the United States?

Childhood immunization series with IPV at 2, 4, 6-18 months, and 4-6 years of age

Which of the following patients should receive one dose of pneumococcal conjugate vaccine (PCV20)?

65-year-old with diabetes who received PPSV23 5 years earlier

Which of the following describes a difference between Tdap and DTaP?

Tdap has a lower dose of diphtheria toxoid for use in individuals aged 10-11 years and older

All women should optimally receive one dose of Tdap when?

Optimally between 27 and 36 weeks gestation of each pregnancy

Which of the following is true regarding the timing of immunization?

Vaccinate two weeks before elective splenectomy or after acute recovery from splenectomy

Which of the following influenza vaccines is produced using no eggs and no influenza virus?

Flublok (RIV4)

Polio is currently considered eradicated worldwide.

False

Which process correctly describes cocooning against pertussis?

Process of vaccinating close contacts including mother, father, siblings, grandparents, and out of home care providers

Which of the following is NOT a permanent contraindication to vaccination?

A condition which would compromise the ability of the vaccine to produce immunity or protection from infection

Per OSHA (Occupational Safety and Health Administration), bloodborne pathogens training must be completed every 2 years for immunizers.

False

Which of the following methods describes how vaccines are covered under Medicare Part D?

Reimbursement based on negotiated amount based on vaccine, dispensing fee, sales tax, and vaccine administration fee

Which of the following is a reporting system by the Institute of Safe Medication Practices (ISMP) to report vaccine administration errors?

VERP

Which of the following skills is among the standards of practice among immunizing pharmacists?

Basic life support (BLS)

Which of the following is a contraindication to receipt of routine vaccines?

Anaphylaxis to a previous dose

Which of the following is true in regards to student pharmacist immunization?

Interns who provide immunizations must be current in CPR and blood borne pathogens training

How should you proceed if vaccine arrives from the manufacturer under questionable conditions?

Store the vaccine as recommended separately from other stock, label with "Do Not Use", and call the manufacturer's quality control office for advice

Pharmacists are an integral part of increasing vaccination rates in the community. Which of the following would be the LEAST effective strategy for a pharmacist to employ?

Recommend that a patient return for a vaccine at a later time when it is less busy

Which of the following is a CDC best practice in regards to vaccine storage and handling?

A bio-safe glycol-based or buffered thermometer should be used to monitor the temperature of the refrigerator

Which of the following statements is true?

Employers must offer the hepatitis B vaccine series to immunizing employees free of charge

Immunocompromised

20mg a day of Steroid for longer than 14 days