Hemophilia A rare disorder that leads to uncontrollable bleeding This is caused by a lack of clotting factors in the blood the disease is genetic and cause by a mutation or absence of the clotting factors which is a gene This is a recessive x-linked disorder (similar to fragile x) Genetic testing for this can be done through a blood test or a search for an inversion Symptoms: uncontrollable bleeding, spontaneous bleeding, prolonged bleeding More general symptoms: nose bleeds, blood in urine, joint pain or swelling, headaches, internal bleeding (mainly in the joints) Treatment: avoid strain on joints, prophylaxis decreases risk of internal bleeding, replacement therapy (replacing the missing clotting factors), a liver transplant (only long-lasting solution, but it isn't foolproof) Prognosis: a little bit of a shorter life-expectancy, without proper treatment people really cannot live into adulthood, more prone to heart disease,liver disease, and so on It can be mild, moderate, or severe There is A and B depending on which gene is affected No cures, but treatment methods can be very successful
Resolution: If I were Maria, I wouldn't consider having a baby until Ron gets tested first. Then as a group, we could determine the percentage that the child has of inheriting the disease. If the chance was very low, I might consider having another child. And if it was high, I would not consider having another child.