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Signal Amplification types
bDNA (branched DNA amplification) - Chiron Corp.
Hybrid Capture Assays
RNA-DNA hybrid capture.
Cleavage-based Amplification.
Cycling probe.
bDNA (branched DNA amplification)
More complex
Solid support
Capture group
Probes
Capture group
Sequence specific DNA and DNA trying to amplify
More probes =
more signals
bDNA goal
increased signal = stronger signal