Signal Amplification

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5 Terms

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Signal Amplification types

  • bDNA (branched DNA amplification) - Chiron Corp.

  • Hybrid Capture Assays

  • RNA-DNA hybrid capture.

  • Cleavage-based Amplification.

  • Cycling probe.

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bDNA (branched DNA amplification)

  • More complex

  • Solid support

  • Capture group

  • Probes

<ul><li><p>More complex</p></li><li><p>Solid support</p></li><li><p>Capture group</p></li><li><p>Probes</p></li></ul><p></p>
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Capture group

Sequence specific DNA and DNA trying to amplify

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More probes =

more signals

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bDNA goal

increased signal = stronger signal