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Grading up
Breeding a purebred males to non-purebred or crossbred females with the goal of making them registerable animals.
Transcription
When mRNA is made from the DNA sequence
Translation
When a protein/enzyme, hormone is made
based on the mRNA sequence
Genome
The entire DNA sequence
Chromosome
DNA organized into long unbroken stands
Locus (plural- loci)
The physical location of a gene of a chromosome
Horses have __ pairs of chromosomes
32 pairs
2n =64
Cattle have __ pairs of chromosomes
30 pairs
2n=60
True or false: Most production traits of economic importance in livestock are quantitatively inherited
True
Phenotype
Realization or observed value of a trait of characteristic of an animal; after removal of systematic environmental effects
Genetic + Environment + Genetic-environment interaction
Genetic=
Additive + Dominance + Epistatic
Mean
Average trait value in population
Variance
How much animals differ from each other in the trait
Without this there will be NO genetic progression
Regression
Predicts offspring performance based of parents measurements
Ex: With chance in weight what is the chance in weaning weight
Correlation
Strength/direction of linear association
Ex: Growth rate and feed efficiency
Covariance
Joint variability
Probability
Parameter space is 0-1
Putting a number on belief
Standard deviation
Square root of the variance (variability) for a collection of records
Standard Error
Square root of the variance (variability) of an estimate of something.
The implication is that although some true value is out there, we estimate it imperfectly unless we have all records from the animals.

____ performance is generally better than purebred performance (not inbred)
Crossbred
Purebred not inbred performance (inbred) is generally better than purebreds that are ____
Inbred
True or false: Animals tend to resemble their parents and other close relatives
True
DNA are considered
beads on a string composed of arranged nucleotides
Purines
Adenine and Guanine
Pyrimidines
Cytosine and Thymine
Full siblings have an average of 50% of their DNA in common in theory, but in practice it varies from?
20 to 70%
Reference genome
Used to compare sequences of nucleotides provides the functional and genomic contexts for regions influenced by selection.
Reference genome for cattle
Hereford
Reference genome for pigs
Duroc
Reference genome for Horses
Thoroughbred
Reference genome for sheep
Rambouillet
Reference genome for goats
San Clemente
Single nucelotide polymorphisms (SNP)
Occur when a single nucleotide is replaced with another
1 SNP for every ___ nucleotides on average
100
Quantitative trait
Only a few genes contribute more than 1% of their genetic variation observed

Autosomal recessive

X- lined recessive

Autosomal dominant

Maternal/mitochondrial
Solid line in arrow diagrams
indicates paternal relationship
Dashed line indicates
Maternal relationship
Additive relationship covariance
Measures the fraction of identical alleles shared by two individuals (on both sets of chromosomes) that were inherited from common ancestors when averaged across all possible segregation outcomes
Parameter space for additive relationship covariance
0-2
(2 is bc of inbreeding)
Sharing of alleles leads to sharing of
Phenotype
Additive relationship covariance of parent and progeny is always
1/2!
Additive covariance between half siblings in absences of other relatedness is
¼ on average
Additive covariance between full siblings in the absence of other relatedness is
1/2
SNP Array
Used to improve accuracy of breeding values (EPD) especially for young males with minimal progeny information
SNP array (Chip) is typically used for
Large scale production or breed associations
SNP arrays for GGP indicus
50k SNPs
Based on Nellore, can be used for primarily Bos indicus breeds
Inbreeding
Mating of related animals
Inbreeding increases __________ throughout the genome
Homozygosity
True or false: Parent offspring mating will generate the highest inbreeding coefficients in animals but not in plants
True
Wrights relationship coefficient
The expected fraction of the DNA that two animals have in common due to common and or direct ancestry

Denominator of the correlation coefficient
The numerator of the relationship represents the additive covariance to two individuals. The denominator standardizes the additive covariance (0 to 2) in the numerator and makes the parameter space (0 to 1)
diploid number for cattle
60
diploid number for cattle
60
Diploid number for Goats
60
Diploid number for horses
64
Diploid number for sheep
54
Diploid number for pigs
38
Composite breed
A breed combining two or more different breeds. Composite breeds are designed to combine desirable traits from multiple breeds, such as growth, fertility, disease resistance, or environmental adaptability.
Estimate standard error
An interval that contains the true amount of DNA shared due to common and or direct ancestry.
1 SE- 0.68
2 SE- 0.95
3 SE- 0.99

Parent to offspring standard error of the relationship coefficient

Inbreeding in dairy: Genetic defects
Lethal recessive and effects on quality and quantities of milk
Genomic test can help manage inbreeding With
parentage verification and genomic inbreeding calculations
Effects of inbreeding on genetic similarities and differences between animals
1) Unrelated inbred animals tend to be more genetically different than unrelated non inbred animals
2) Related inbred animals will have genetic similarities; however, they will have genetic differences due to inbreeding
3) Offspring and Declan dates of inbred animals tend to be more genetically similar than offspring/ descendants of non inbred animals
Horned
Animal possesses horns (attached to the skull)
Polled
Animals in naturally hornless (born without horns)
Scurred
Irregular horn like coverings, smaller than full horns
Knobs
Cone shaped protrusions from the skull. Often hidden by wool
Up ears
Ears that point upward
Down ears
Ears that hang or point downward
Bos Taurus Breeds
Europe
Temperate climates
Low heat tolerance
Earlier puberty
Higher meat quality
No prominent hump
Bos Indicus breeds
India
Tropical climates
High heat tolerance Earlier
Later puberty
More moderate meat quality
Prominent hump
Paternal
Sire/father traits
larger
Fast growth
Good carcass
Good marbling/carcass yield
Feed efficient
Heavy muscling
Maternal
Mother traits
Moderate size
Good fertility
Prolific- produces lots of offspring
Good milk production
Adaptable
Low maintenance
Angus
Bos Taurus, British breeds
Origin- Scotland
• Color- Black
• Horn status - Polled
• Important fact(s)/key characteristic(s)-
Industry standard for marbling
Excellent udder soundness
Frequently used for grading up
Paternal
Red Angus
Bos taurus, British breeds
Origin- Scotland
• Color- Red
• Horn status- Polled
• Important fact(s)/key characteristic(s)-
Similar to Angus
Generally more moderate size than Angus
Hereford
Bos Taurus, British breeds
Origin- England
• Color- Red with whiteface/Hereford pattern (white on the face, underline, feet, and switch)
• Horn status (horned, polled, etc.)- Horned or polled
• Important fact(s)/key characteristic(s)-
Hardy and adaptable
Good early maturity/fattening
Decent meat quality
More prone to cancer eye because of white face
Paternal
Shorthorn
Bos Taurus, British breeds
• Origin- England
• Color- Red, red roan, white
• Horn status (horned, polled, etc.)- Horned or polled
• Important fact(s)/key characteristic(s)-
Good marbling
Less muscular than other British breeds
Quiet disposition
First breed association in America — 1870
South Devon
Bos Taurus, British breed
Origin- England
• Color- traditionally red; can also be black through grading up
• Horn status (horned, polled, etc.)- Horned or polled
• Important fact(s)/key characteristic(s)-
Largest British breed
Excellent beef traits and maternal traits
Adaptable
Charolais
Bos Taurus
Continental European beef breeds
Origin- France
• Color- White, straw, or red
• Horn status (horned, polled, etc.)- Horned or polled
• Important fact(s)/key characteristic(s)-
Heavy muscling
Red only eligible for registration in the redfactor herd book NOT purebred herdbook
Only white/straw accepted for purebred registration
Simmental
Bos taurus, continental European beed breeds
Origin- Switzerland
• Color- Traditionally red or straw with a bald face and spotting or completely red; black or black with varying amounts of white (Can be black because of grading up.)
• Horn status (horned, polled, etc.)- Horned or polled
• Important fact(s)/key characteristic(s)-
Heavy muscling
Rapid growth
Good feed efficiency & milk production
Gelbvieh
Bos Taurus, continental European beed breeds
Origin- Germany
• Color- Red; can also be black
• Horn status- Horned or polled
• Important fact(s)/key characteristic(s)-
Heavy muscling
Excellent mothering instincts
Limousin
Bos Taurus, continental European beef breeds
Origin- France
• Color- Traditionally red; black (Can be black because of grading up.)
• Horn status - Horned or polled
• Important fact(s)/key characteristic(s)-
Heaviest muscled continental breed
High carcass yield
Good growth rate
Chianina
Bos Taurus, continental European beef breed
Origin- Italy
• Color- Gray with black pigmentation
• Horn status (horned, polled, etc.)- Horned or polled
• Important fact(s)/key characteristic(s)-
Largest frame continental breed
Tallest cattle breed
Heavy muscling
Low marbling
Braunviech “Brown Swiss”
Bos Taurus, Continental European beef breeds
Switzerland
• Color- Various shades of brown
• Horned or polled?- Horned or polled
• Important fact(s)/key characteristic(s)-
Dual purpose: milk + meat
Good feet
High butterfat milk
Maine- Anjou
Bos Taurus, continental European beef breeds
• Origin- France
• Color- Originally red/red-white; can be black
• Horn status (horned, polled, etc.)- Horned or polled
• Important fact(s)/key characteristic(s)-
Good feed efficiency
Good carcass traits
Tarentaise
Bos Taurus, continental European beef breeds
Origin- France
• Color- Red with darker pigmentation around eyes; can be black
• Horn status (horned, polled, etc.)- Horned or polled
• Important fact(s)/key characteristic(s)-
Excellent muscling in hip region
Long from hooks to pins
Adapted to mountainous environments
Salers
Bos Taurus, continental European beef breeds
Origin- France
• Color- Dark red; can be black
• Horn status (horned, polled, etc.)- Horned or polled
• Important fact(s)/key characteristic(s)-
One of the oldest/genetically pure European breeds
Hardy
Nellore
Bos indicus, Beef breed
Origin- India
• Color- Gray with black pigmentation
• Horn status (horned, polled, etc.)- Horned or polled
• Important fact(s)/key characteristic(s)-
Hardy
Heat & Insect resistant
Good udders
Very few in U.S.
Brahman
Bos indicus, beef breeds
Origin- U.S. origin from cattle that originated in India
• Color- Red or gray
• Horn status (horned, polled, etc.)- Horned or polled
• Important fact(s)/key characteristic(s)-
Heavy muscling
Excellent heat & insect resistance
Very important in Southern U.S.
Boran
Bos indicus, beef breeds
• Origin- Ethiopia
• Color- Red or gray with dark pigmentation
• Horn status (horned, polled, etc.)- Horned or polled
• Important fact(s)/key characteristic(s)-
Good milk production
Highly fertile
Earlier maturity
Docile
Brangus
Composite breed
5/8 angus + 3/8 Bos indicus
Origin- U.S.
• Color- Black
• Horn status (horned, polled, etc.)- Polled
• Important fact(s)/key characteristic(s)-
Good mothers
Hardy
Combines:
Angus → meat quality
Bos indicus → heat tolerance
Beefmaster
Composite breed
½ Brahman + ¼ Hereford + ¼ shorthorn
• Origin- U.S.
• Color- Various colors
• Horn status (horned, polled, etc.)- Horned or polled
• Important fact(s)/key characteristic(s)-
Hardy
Typically selected for the Six Essentials:
Weight
Conformation
Milking ability
Fertility
Hardiness
Disposition
Santa Gertrudis
Composite breed
3/8 Brahman & 5/8 shorthorn
Origin- U.S. (Kingsville, TX)
• Color- Deep Red
• Horn status : Horned or polled
• Important fact(s)/key characteristic(s)-
Heat resistant
Tick resistant
Good milk production
Strong mothering
Simbrah
Composite breed
Origin- U.S. (Gulf coast)
• Color- Many colors
• Horn status- Horned or polled
• Important fact(s)/key characteristic(s)-
Good heat tolerance
Good maternal traits
"All-purpose American breed“
Brahford
3/8 Brahman + 5/8 Hereford
Origin- U.S.
• Color- Brindle, red, chocolate, etc
• Horn status- Horned or polled
• Important fact(s)/key characteristic(s)-
Excellent maternal traits
Good calving ease
Good milk
Strong mothering
Long productive life
Droughtmaster
Composite breed
½ shorthorn + ½ Brahman
• Origin- Australia
• Color- Red
• Horn status (horned, polled, etc.)- Horned or polled
• Important fact(s)/key characteristic(s)-
Lean carcasses
Heat/drought adapted