Immune System

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9 Terms

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T cell

kill by contact, cellular immune response

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B cells

produce antibodies, humoral immune response

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Natural Killer (NK) cells

destroy cells by releasing perforins and granzymes

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Macrophages

Eat cells; bridge between innate and adaptive immunity

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Dendritic cells (DC)

Antibody presenting cells of the mammalian immune system

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CD4 mediated response

non-specific, MCH II antigen complex. Releases cytokines—> can activate B-cells. “Helper”

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CD8 mediated response

produces perforins and granzymes. "Cytotoxic”

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Toll-like receptors (TLRs)

recognize damage and trigger inflammation pathways (NF-KB, AP-1)

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CAR T

Engineering patient’s immune cells to treat their cancers