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Anton van Leeuwenhoek
Discovered, and observed microorganisms with a microscope
Louis Pasteur
Proved microorganisms, cause fermentation and help disprove spontaneous generation (microbes come from other microbes)
Robert Koch
Proved that specific microbes cause specific disease
Ignaz Semmelweis
Showed that handwashing could prevent the spread of infection/disease
Joseph Lister
Introduced antiseptic methods to prevent infection during surgery