Patient-Controlled Analgesia; IV administration system where patient initiates small opioid dose by pressing button; includes lockout period and dosing controls
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Morphine (Opioid) - Why
Suppresses pain; used for anesthesia
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Morphine (Opioid) - MOA
Acts on opioid receptors in CNS; causes euphoria and sedation
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Opioid Adverse Effects
Respiratory depression (body less responsive to CO2), increased risk with respiratory disorders, hypotension, nausea/vomiting, constipation
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Naloxone (Opioid Antagonist) - Why
Reverses effects of opioids
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Naloxone (Opioid Antagonist) - MOA
Strongly binds to opioid receptors but does not activate them