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Hyaline cartilage
Glassy matrix, fine collagen; reduces friction; nose, trachea, ribs, joints.

Fibrocartilage
Thick collagen fibers; resists compression; intervertebral discs, pubic symphysis, menisci.

Elastic cartilage
Elastic fibers + collagen; flexible support; ear and epiglottis.
Chondroblasts
Cartilage‑forming cells that produce matrix.

Chondrocytes
Mature cartilage cells housed in lacunae.

Lacunae
Small spaces that contain chondrocytes or osteocytes.

Extracellular matrix (Cartilage)
Protein fibers + ground substance surrounding cartilage cells.
Perichondrium
Dense connective tissue covering cartilage; contains stem cells.
Cartilage functions
Supports soft tissues, provides smooth surfaces, models bone formation.
Bone functions
Support, protection, movement, mineral/energy storage, blood cell formation.
Long bones
Longer than wide; act as levers; femur, humerus.

Short bones
Cube‑shaped; stability; carpals, tarsals.

Flat bones
Thin, flat; protect organs; skull, sternum.

Irregular bones
Complex shapes; vertebrae, pelvis.

Compact bone
Dense outer bone providing strength.
Spongy bone
Porous bone with trabeculae; houses marrow.

Proximal epiphysis
End of bone closest to body trunk.

Distal epiphysis
End of bone farthest from trunk.

Diaphysis
Shaft of long bone.

Metaphysis
Region between diaphysis and epiphysis.

Epiphyseal line
Remnant of growth plate.

Articular cartilage
Hyaline cartilage covering joint surfaces.

Medullary cavity
Central cavity containing marrow.

Endosteum
Lining of medullary cavity; contains bone cells.

Periosteum
Outer covering of bone; anchors tendons/ligaments.

Perforating fibers
Collagen fibers attaching periosteum to bone.

Nutrient foramen
Opening for blood vessels and nerves.

Yellow bone marrow
Fat storage tissue.

Red bone marrow
Site of blood cell formation.

Osteoprogenitor cells
Stem cells that produce osteoblasts.

Osteoblasts
Bone‑forming cells that secrete matrix.

Osteocytes
Mature bone cells maintaining matrix.
Osteoclasts
Bone‑resorbing cells that break down matrix.

Organic matrix
Collagen + proteins; gives flexibility.
Inorganic matrix
Calcium phosphate crystals; gives hardness.
Osteon
Structural unit of compact bone.

Central canal
Canal for blood vessels and nerves.

Lamellae
Concentric rings of matrix.

Canaliculi
Channels connecting lacunae.

Perforating canal
Connects central canals across osteons.

Trabeculae
Lattice‑like bone structures.

Intramembranous ossification
Bone develops from mesenchyme; forms flat bones and clavicle.
Endochondral ossification
Bone replaces cartilage model; forms most bones.
Interstitial growth
Lengthwise growth at epiphyseal plate.

Appositional growth
Width growth via periosteum.

Fracture repair stages
Hematoma → soft callus → hard callus → remodeling.
Osteomalacia
Soft bones due to vitamin D deficiency; rickets in children.

Osteoporosis
Bone density loss due to aging, hormones, or inactivity.