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What is the effect on lymph flow rate through the lymph node caused by the fact that there are fewer efferent relative to afferent lymphatic vessels?
Slower because more afferents than exits(efferents)
Which set of lymphatic vessels carries the lymph away from the node? Afferent or efferent?
efferent
Which lymph duct drains lymph from the right side of the body and
which duct drains lymph from the upper left quadrant of the body?
Which blood vessels do these lymph ducts return the lymph, respectively.
- Right: Right lymphatic - right subclavian vein
- Left: thoracic - left internal jugular vein
In what organ do B and T lymphocytes originate and in what organ do they mature?
B Cells - Bone marrow, Bone marrow
T cells - Bone marrow, thymus
name 3 types of tonsils and where they are located. For example, palatine tonsils located near the palate.
- palatine tonsils – posterior end of the oral cavity (largest and most often affected)
- lingual tonsil – lumpy collection of follicles at base of tongue
- pharyngeal tonsil (adenoids) – posterior wall of nasopharynx
What cytokine do virus-infected cells secrete and what is effect on other cells?
- interferon
- apoptosis
By what mechanism do natural killer cells (NK) “kill” target cells such as cancer cells?
-apoptosis
Name the 3 types of T cells (for example helper )
- T cells
- regulatory
-cytotoxic
Where and how is the lymph created and identify the lymphatic vessel pathway returning lymph to the blood starting with the lymphatic capillaries
- Once interstitial fluid enters lymphatic capillaries, it becomes lymph
- lymphatic capillaries - collecting vessels - lymphatic trunks - collecting ducts - subclavian veins - Right atrium
How much lymph is created and returned to the blood every 24 hrs.
20L
Name 1) the lymphoid organs and 2) areas of lymphoid tissue that are not organs.
-bone marrow, thymus
• malt, tissues, tonsils
What is the difference between passive and acquired immunity?
Passive-through mother, goes away after amount of time
• Acquired- vaccine, stays and adapts immune cells
What are the primary functions of the B lymphocyte? Are these cells limited to binding only one antigen on their receptors?
-Produces antibodies
• They are pathogen specific
Describe the main mechanisms involved in inflammation such as swelling
- Increase in fluid caused by immune cells cause inflammation such as swelling
- redness, heat, swelling, pain
What are the functions of the nasal conchae?
Increase surface area of the cavities, provides rapid warming and humidification of air as it passes to lungs
In chronic bronchitis, what causes the dyspnea associated with this condition?
How is mucus affected?
Inability to expirate
Always for air to flow
• Emphysema
What controls the voice pitch and what controls voice loudness?
length and tension of vocal cords
What is the function of type II alveolar cells?
- secrete surfactant
Is normal, quiet expiration of air an active or a passive process?
passive
For what 2 factors related to respiration does Boyle’s law address a relationship?
Pressure and volume
Is a decrease in Oxygen or an increase of carbon dioxide the most powerful driver for breathing in a healthy person?
- carbon dioxide
What is the quantity of oxygen by percentage in plasma? Is it similar to that associated with red blood cells? What molecule in red blood cells carries oxygen and what element within that molecule actually binds to oxygen?
-1-5%
-Hemoglobin
-iron
Define tidal volume in relation to breathing
measures the amount of air that is inspired and expired during a normal breath
What happens to hemoglobin oxygen saturation at high altitudes?
decreases
What is the major means of chyme, urine and ova propulsion in the small intestine, ureter and oviduct respectively?
peristalsis
Are most nutrients absorbed by the intestinal microvilli in an active process or by a passive diffusion process?
Passive diffusion
Which part of the digestive tract is least involved in mechanical food breakdown, digestion or absorption? In other words, functions primarily as a conducting tube
-esophagus
Where is alcohol rapidly absorbed along the alimentary canal?
-stomach
What is emulsification and what agents contributes to it and where are these agents initially produced?
• Bile, in the liver
Why could a ruptured appendix be life-threatening? By what mechanism?
- formation of scar tissue, strangulated organs
• Release bacteria in peritoneum, so could get peritonitis, inflammation and could potentially penetrate some of our organs
Is the absorption of lipids (fat) in the small intestine an active transport or a passive diffusion through the intestinal epithelial cells?
-passive
which stomach cells secrete acid and which cells secrete pepsinogen?
-parietal cells
If the GFR is low, does the rate of tubular reabsorption increase or decrease?
-decrease
What is the structural urine elimination pathway from the kidney hilum to the outside?
- ureter, bladder, urethra
What is the function of mitochondria
and how might this affect active transport processes such as Na K ATPases?
• Energy drivers
During an urinalysis, the technician finds protein in a patients urine sample.
What could cause this?
- Damage to glomerulus
If cells and proteins are prevented physically from passing through the filtration membrane, what is the osmotic effect on filtration? Is filtration across membrane increased or decreased?
-increased
What are the differences between extrinsic and intrinsic control of the kidneys? Give an example of each.
Extrinsic- involve hormones like renin, in response for low blood pressure for one • Intrinsic- involve regulation of pressure going in and out of globular, local control
What active co-transporter molecules are responsible for glucose and amino acid reabsorption and where in the kidney tubules does this take place?
Sodium-glucose cotransporters, proximal tubule
Establishment of the medullary osmotic gradient (increases from the cortex through the medulla) is dependent on the unique permeability properties of_____________?
Nephron loop
What stimulus causes the kidney to produce renin?
Low blood pressure
.What is the primary force driving filtration from the capillary blood across the filtration membrane in the glomerulus?
Hydrostatic pressure
The two semilunar valves of the heart are:
. The aortic and pulmonary valves
The electrical signal initiating each heartbeat is generated at the:
Sinoatrial node
What is the protective temperature of the testes relative to 37degree C body temperature? What would be the effect if the testes temperature attained body temperature?
- 3* under body temperature
-sperm would die
. Does the number of ovarian follicles containing immature eggs drastically increase at puberty?
All eggs present at birth
decrease
Does spermatogenesis start at birth in males?
-no, at puberty
What is the primary role of the dartos and cremaster muscles in the male?
Maintain temperature of testicles
By what mechanism does the combination of estrogen and progesterone in birth control pills prevent ovulation?
- Negative feedback
Milk ejection from the mammary glands is stimulated by which posterior pituitary hormone?
oxytocin
What force moves sperm along the vas deferens?
- peristalsis
What changes in estrogen and progesterone blood levels trigger the onset of menstruation?
Both decreased
What hypophyseal hormone controls the release of FSH and LH from the anterior pituitary?
- gonadotropin
Where in the uterine tubes(oviducts) does fertilization take place?
- ampulla
Which of the sexually transmitted diseases is incurable?
- Herpes & Aids
. What natural chemical produced by endothelium is essential for erection of the penis to occur?
nitric oxide
What hormone maintains the viability of the corpus luteum during pregnancy
- HCG
What hormone detected in a urine pregnancy test would indicate a successful implantation and pregnancy?
-HCG
What acrosomal enzyme on cell surface of sperm acts to digest connection between granulosa cells of the oocyte, causing them to separate during fertilization
• hyaluronidase
What triggers the ovum to complete meiosis II?
- when sperm first attaches
- • fertilization
Which is the earlier stage – morula or blastocyst?
marula
What hormone maintains the corpus luteum?
progesterone
. What happens if the levels of estrogen and progesterone fall?
menstruation, pregnancy ends
HCG Blood levels slowly increase from week 2 of pregnancy to birth T or F ?
false