Solid organ transplantation (cont’d)

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4 Terms

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What are alloantigens?

are antigens that differ between individuals of the same species.

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What happens when a transplanted tissue contains different MHC molecules?

The MHC molecules may be recognized as foreign, activating an adaptive immune response.

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What is transplantation rejection?

occurs when the recipient's immune system targets donor tissue alloantigens.

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How can transplantation rejection be prevented?

Rejection can be prevented via proper HLA typing and the use of immunosuppressive drugs.