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HEPA filters are used to remove microbes from what?
Air
Swabbing the skin with an alcohol prep pad prior to injection is an example of:
Antisepsis
Chlorine is what type of substance used to disinfect water?
Halogen
Which are the most resistant infectious organisms/particles?
Endospores
Antimicrobial agents work better under what conditions?
High temperature
How is sterilization achieved?
Steam autoclave
Which microbial control method specifically targets the microorganisms on living tissues, often using antimicrobial agents?
Antisepsis
Which term describes a microbial control agent that destroys bacteria?
Bactericide
Which types of microorganisms are known for their exceptional resistance to many antimicrobial methods, making them the standard target for sterilization?
Bacterial endospores
Which method of physical control of microorganisms involves using UV light to damage the DNA of pathogens, inhibiting their replication and survival?
Non-ionizing radiation
Which method of physical control involves the removal of moisture from microorganisms, preventing their metabolic activities and potentially leading to their death?
Desiccation
_____ heat is more rapidly effective and efficient compared to _____ heat.
Moist; dry
Antimicrobials dissolved in pure alcohol or water-alcohol solutions are called:
Tinctures
What class of chemical agents disrupts cell membranes?
Detergents
Which microorganism is the primary target for azole drugs?
Fungi
What is the primary factor contributing to the development of antibiotic resistance among bacterial populations?
Overuse of antibiotics
Which events lead to the development of antibiotic resistance in bacteria?
Horizontal gene transfer, such as conjugation and spontaneous mutations in bacterial chromosomes
Which antibiotic, considered a narrow-spectrum drug, is primarily effective against mycobacteria?
Polymyxin
Which antibiotic functions by inhibiting bacterial protein synthesis at the 50S ribosomal subunit?
Azithromycin
Which is not a mechanism of drug resistance?
Mutations in target genes
Which antibiotic is considered a broad-spectrum drug?
Tetracycline
A patient presents with mild cold symptoms and, despite the viral nature of the illness, the physician prescribes a broad-spectrum antibiotic. This scenario is an example of what?
Overuse of antibiotics
What process allows bacteria to acquire antibiotic-resistance genes from other bacteria, often through mechanisms like conjugation, transformation, or transduction?
Horizontal gene transfer
A patient presents with a fungal skin infection. Which drug choice is the most appropriate for treatment?
Ketoconazole
Which antimicrobials are effective against a wide variety of microbial types?
Broad-spectrum drugs
Which of the following is a mechanism of antibiotic resistance?
Increased removal of drug from cell
Some antibiotics inhibit a crucial metabolic pathway in bacteria, preventing the synthesis of an essential molecule. Which metabolic pathway is targeted by antibiotics like sulfonamides and trimethoprim?
Folic acid synthesis
Antiviral drugs that interfere with the release of new virus particles from infected cells typically fall into which category of action?
Block exit
What is the term for the objective evidence of disease noted by an observer?
Sign
Which term is used to describe the community of microorganisms that inhabit a specific environment, such as the human body, often living in symbiosis with the host?
Microbiota
Which mode of disease transmission occurs from mother to child via the placenta or milk?
Vertical transmission
Babies acquire their microbiota from many sources, but not from:
Bug bites
When an infection is localized at a specific site in the body and may serve as a source spreading to other tissues or organs, what is it called?
Focal infection
What term describes insect vectors that carry microbes on their bodies?
Mechanical vectors
In which pattern of infection does the pathogen spread throughout the body, affecting multiple organs and tissues, often leading to severe illness?
Systemic infection
Within the human microbiota, some microorganisms typically exist as harmless residents but can become pathogenic under certain conditions, causing infections. What term best describes these microorganisms?
Opportunistic pathogens
In the progression of infectious diseases, which stage is characterized by the appearance of mild, non-specific symptoms that often precede the full onset of the disease and may serve as an early warning sign?
Prodromal
What is the term for a toxin that is a component of the outer membrane of certain Gram-negative bacteria and is released when the bacteria are damaged or die, contributing to symptoms of infection?
Endotoxin
What bacterial structure is known to protect pathogens from phagocytosis by host immune cells?
Capsule
How do most humans primarily acquire their initial microbiota during birth?
Passage through the birth canal
After caring for a patient with an infectious disease, a healthcare worker touches and contaminates a doorknob. A colleague later touches the doorknob and then touches their face, leading to an infection. What term best describes the inanimate object that served as the intermediary in this transmission?
Fomite
A nurse working in the medical surgical unit of the hospital is most likely to be what kind of infectious agent carrier?
Passive
What is the purpose of the Centers for Disease Control and Prevention (CDC)?
Protect public health
When is an infectious disease classified as an endemic?
Cases occur frequently in one geographic location
What is the study of the frequency and distribution of a disease in a defined population called?
Epidemiology
When is an infectious disease outbreak classified as an epidemic?
There are more instances of a disease than expected.
How would an epidemiologist classify a scenario where several people develop food poisoning several hours after eating hamburgers at a barbecue?
Point-source epidemic
The total number of human immunodeficiency virus (HIV) infected individuals living in the United States is described using what term?
Prevalence
In 2020, the world was stunned by the appearance of COVID-19. How would you categorize the rise of this disease?
Emerging
In 2009, there were more cases of influenza than expected due to a new viral strain called H1N1. This outbreak is described as what?
Epidemic
The virus that causes COVID-19 spreads by direct and indirect contact from person to person. How would you categorize an epidemic that spreads through a community in this manner?
Group epidemic
Point-source epidemic
Common-source epidemic
Propagated epidemic
What term describes the number of new cases of a disease over a specific period of time?
Incidence
The prevalence rate of tuberculosis in one particular county in Texas is 7/1000 people, while the incidence rate for 2011 is 2/1000 people. Analyze this data and summarize the situation.
Prevalence rate is higher because it includes all tuberculosis cases, including the newly infected people counted in the incidence rate.
The numbers of infectious diseases are increasing in part due to infections caused by antibiotic-resistant bacteria. In the past, these microbes were not resistant to antibiotics and were easily destroyed by antibiotics. How would you classify the increasing prevalence of diseases caused by antibiotic-resistant bacteria?
Reemerging
What conditions led to the classification of COVID-19 as a pandemic?
The detection of COVID-19 infections on more than one continent
The disease, Dengue fever, is endemic in Central and South America. A recent case of Dengue fever in Los Angeles, CA would be classified as what?
Sporadic
The first person infected in an epidemic is the what?
Index case