Post-translational Control

What is post translational control?

Modifying the polypeptides to make proteins of specific functions.

Adding non protein groups

- Lipoprotein, glycoprotein

Modify amino acids to make bonds

We can change an amino acid to cysteine, to form disulphide bridges

What are tertiary structures?

3D structure of protein

What are quaternary structures?

Combination of subunits

Protein folding

Tertiary or quaternary structures

Modification by cAMP

cAMP + CRP

This complex can bind to RNA polymerase to help regulate activity.

cAMP activate kinases. These activated kinases can then phosphorylate and activate other enzymes & proteins.