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What are the subunits of microtubules?
GTP-ab tubulin heterodimer
What are the subunits of intermediate filaments?
~70 different proteins
What are the subunits for microfilaments?
ATP-actin monomers
What is the preferential site of incorporation for microtubules?
+ end (B tubulin)
What is the preferential site of incorporation for intermediate filaments?
Internal
What is the preferential site of incorporation for microfilaments?
+ end (barbed)
Are microtubules polar?
Yes
Are intermediate filaments polar?
No
Are microfilaments polar?
Yes
What is the enzyme for microtubules?
GTPase
What is the enzyme for intermediate filaments?
N/A
What is the enzyme for microfilaments?
ATPase
What are the motor proteins for microtubules?
Kinesins and dyneins
What are the motor proteins for intermediate filaments?
N/A
What are the motor proteins for microfilaments?
Myosin
What are the proteins associated with microtubules?
MAPs
What are the proteins associated with intermediate filaments?
Plakins (i.e. plectin)
What are the proteins associated with microfilaments?
Actin-binding proteins
What are the dimensions of microtubules?
25 nm (unbrnached)
What are the dimensions of intermediate filaments?
10-12 nm (unbranched)
What are the dimensions of microfilaments?
7-8 nm (branched)
What is the primary function of microtubules?
Support, intracellular transport, and cell organization
What is the primary function of intermediate filaments?
Structural support
What is the primary function of microfilaments?
Motility, contractility, and intracellular transport
