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Systemic Circuit
Carries blood throughout body to supply oxygen and nutrients to tissues
Pulmonary Circuit
Larger loop that carries blood to the lung for gas exchange
Arteries/Artery
Cary blood away from the heart
Branch to form arterioles
Venules and Veins
Carry blood back toward heart
Venules and Veins
Exposed to lower pressures
Capillaries
are the sites of exchange
Lumen
Space blood flows
Valves
ensures one-way flow
Tunics
blood vessel walls
tunica intima
innermost layer
Atherosclerosis
tendency for blood to clot
prone of clotting
lamina
internal elastic membrane
Large arteries
not found in veins
provides additional elasticity
Tunica media (middle layer)
mainly smooth muscle
Tunica externa (outermost)
mainly of collagen
maintains structure of vessel
Vasa vasorum
supplied by larger arteries and veins
Arteries
away from the heart
oxygenated
Elastic arteries
higher percentage of elastic fibers
help propel blood
muscular arteries
higher percentage of smooth muscle
controlling distribution of blood
arterioles
Microscopic arteries
very thin
greatest resistance to blood flow and blood pressure
capillaries
thin-walled vessels
used for exchange between blood and tissue
continuous
most common type, complete
allows exchange of water
fenestrated
found in small intestine & kidneys
contain pores in endothelial lining
allows exchange of fluid
sinusoid (al)
found in liver
least common
large gaps
allow exchange of plasma proteins and cells
metaterioles
regulate flow of blood into capillary beds
located at openings of capillary beds
sphincters
contract to limit blood flow
venules
extremely small veins
veins
toward the heart
thinner walls than arteries
artery-arteriole-capillary bed-venule-vein
Typical pattern of blood flow:
arterial anastomosis
multiple arteries
provides alternate routes
venous anastomosis
venule split, contribute to multiple veins
portal system
links two capillary beds
blood flow
movement of blood through the body
arterial blood pressure
measured using a sphygmomanometer at the brachial artery
Systolic pressure
ventricular systole
Diastolic pressure
ventricular diastole
pulse pressure
difference between systolic and diastolic pressure
ex: 120/80
120-80=40 the answer
mean arterial pressure
“average” pressue, calculated
pulse
the expansion
cardiac output
amount of blood rejected
blood volume
amount of blood within vascular
poiseville’s equation
relates resistance to blood flow
blood vessel length, blood viscosity etc.
Blood Viscosity
The thickness of blood
blood vessel radius
inversely proportion to resistance
vessel radius
most important influence on resistance
compliance
to expand
blood velocity
speed of flow
hypertension
defined by high blood pressure greater than 140/90
ductus venosus
bypass liver
epinephrine and novepinephrine
increase BP via increased CO
Aldosterone
increases blood volume to increase BP
Atrial natriuretic hormone
decreases blood volume to decrease BP
parasympathetic
if BP is too high
sympathetic
if BP is too low
baroreceptor reflexes
balancing the BP if its too high or too low
vasomotor
control vascular tone
cause vasoconstriction (vasodilation)
Cardioinhibitory
decrease HR
via parasympathetic
cardioaccelerator
regulate heart rate HR
increase HR
lymphatic capillaries
absorb excess to prevent edema