Skin Tumor Cyst AND Scarring

Keratinocyte tumors

SebK, actinic keratosis, Bowen, BCC, SCC

Melanocyte tumors

Nevus, melanoma

Which layers of skin have LIVING cells

granulosum, spinosum, basale

Benign skin tumors

SebK, moles/nevus

Premalignant skin tumors

Actinic keratosis, Bowen disease

Malignant skin tumor

BCC, SCC, MM

Stuck on

SebK

What is Leser Trelat sign

Sudden eruption of many SebK lesions → Indicates malignancy

Actinic keratosis

Risk of SCC in actinic keratosis

0.1-20% per year

Bowen disease

What is Bowen disease

Intraepidermal carcinoma in situ (only in that area)

Causes of Bowen disease

UV radiation, HPV (HPV16), arsenic, immunosuppresion

Nodular BCC

Pigmented nodular BCC

SCC

What conditions can become SCC

Actinic keratosis, Bowen disease

Risk factor of SCC

Chronic sun exposure, chronic wound (Marjolin ulcer), immunosuppresion, HPV (genital), smoking and arsenic

Pathophysiology of SCC

UV damage cause p53 mutation

Histology of SCC

Common mole

What is the ABCDE of melanoma

Asymmetry, Border (irregular), Color (varied), Diameter (larger than 6mm), Evolution (changes over time)

Nevus (congenital, melanocytic nevus at nail, blue nevus)

Melanoma

Melanoma

Epidermal inclusion cyst

Cause of epidermal inclusion cyst

From infundibulum of hair follicle; has white stinky keratinous material inside

Dermoid cyst

What causes dermoid cyst

Trapped ectoderm in embryogenesis that has mass in infant and children