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Vocabulary flashcards based on the lecture notes about chemical signals in animals.
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Hormone
A chemical signal secreted into the circulatory system that communicates regulatory messages within the body.
Target cells
Cells equipped to respond to a specific hormone due to the presence of receptors.
Nervous system
A system that conveys high-speed electrical signals along neurons to regulate other cells.
Endocrine system
A system that secretes hormones to coordinate slower but longer-acting responses.
Neurons
Specialized cells that convey electrical signals in the nervous system.
Paracrine signaling
Local signaling where target cells lie near the secreting cells.
Autocrine signaling
Local signaling where the target cell is also the secreting cell.
Endocrine signaling
Hormones secreted into extracellular fluids by endocrine cells, reaching targets via the bloodstream.
Synapses
Specialized junctions where neurons form connections with target cells.
Neurotransmitters
Chemicals secreted by neurons at synapses that diffuse short distances to bind to receptors on target cells.
Neuroendocrine signaling
Specialized neurosecretory cells secrete neurohormones that travel to target cells via the bloodstream.
Neurohormones
Hormones made by neurons. Unlike neurotransmitters which act locally, neurohormones enter the bloodstream.
Amines
Hormones derived from amino acids.
Polypeptides
Hormones consisting of proteins and peptides.
Steroid hormones
Lipid-soluble hormones with a specific four-ring structure.
Lipid-soluble hormones
Hormones that pass easily through cell membranes (e.g., steroid hormones).
Water-soluble hormones
Hormones that do not pass easily through cell membranes (e.g., polypeptides and amines).
Exocytosis
Secretion of water-soluble hormones from a cell.
Diffusion
The method by which lipid-soluble hormones cross cell membranes.
G protein-coupled receptor (GPCR)
A receptor on the outside of the cell that epinephrine binds to.
G protein
A protein inside the cell that is activated when epinephrine binds to GPCR.
Adenylyl cyclase
An enzyme in the membrane that converts ATP to cAMP.
cAMP
Cyclic adenosine monophosphate, a second messenger that carries signals inside the cell.
Protein Kinase A (PKA)
An enzyme that adds phosphate groups to other proteins (phosphorylation).
Adrenergic receptor
A type of GPCR that epinephrine (adrenaline) binds to.
Transcription factors
Protein-receptor complexes that regulate gene transcription in the nucleus.
Endocrine glands
Ductless organs where endocrine cells are grouped together.
Exocrine glands
Glands that have ducts and secrete substances onto body surfaces or into cavities.
Hypothalamus
The portion of the brain that contains a number of small nuclei with a variety of functions.
Pituitary gland
A gland attached to the hypothalamus, composed of the posterior and anterior pituitary.
Neurohormones
Hormones synthesized and secreted by the hypothalamus that stimulate or inhibit the secretion of pituitary hormones.
Simple hormone pathways
Hormones are released from an endocrine cell, travel through the bloodstream, and interact with specific receptors within a target cell to cause a physiological response
Simple neuroendocrine pathways
The stimulus is received by a sensory neuron, which stimulates a neurosecretory cell that releases a neurohormone into the bloodstream.
Negative feedback
A feedback loop that inhibits a response by reducing the initial stimulus.
Positive feedback
A feedback loop that reinforces a stimulus to produce an even greater response.
Posterior pituitary
Stores and secretes hormones that are made in the hypothalamus.
Anterior pituitary
Makes and releases hormones under the regulation of the hypothalamus.
Oxytocin
A neurohormone secreted by the posterior pituitary that regulates milk secretion.
Antidiuretic hormone (ADH)
A neurohormone secreted by the posterior pituitary that regulates physiology and behavior.
Prolactin (PRL)
A hormone secreted by the anterior pituitary that has a role in milk production.
Tropic hormones
Hormones that target other endocrine glands, causing them to release more hormones.
Nontropic hormones
Hormones that act directly on non-endocrine tissues.
Portal vessels
Capillary network/portal system connects the hypothalamus and anterior pituitary directly, allowing hormones to travel efficiently from one to the other
FSH (Follicle-stimulating hormone)
A tropic hormone that targets the testes or ovaries.
LH (Luteinizing hormone)
A tropic hormone that targets the testes or ovaries.
TSH (Thyroid-stimulating hormone)
A tropic hormone that targets the thyroid.
ACTH (Adrenocorticotropic hormone)
A tropic hormone that targets the adrenal cortex.
Prolactin
A nontropic hormone that acts on mammary glands to stimulate milk production.
MSH (Melanocyte-stimulating hormone)
A nontropic hormone that acts on melanocytes in the skin.
GH (Growth hormone)
A hormone with both tropic and nontropic effects, acting on tissues like bones and liver.
Thyroid hormone
A hormone that results from a hormone cascade pathway involving the hypothalamus, anterior pituitary, and thyroid gland.
TRH
Thyrotropin-releasing hormone, secreted by the hypothalamus.
Parathyroid hormone (PTH)
A hormone released by the parathyroid glands that regulates calcium levels in the blood.
Calcitonin
A hormone released by the thyroid gland that regulates calcium levels in the blood.
Adrenal glands
Glands adjacent to the kidneys, consisting of the adrenal medulla and adrenal cortex.
Adrenal medulla
The inner portion of the adrenal gland.
Adrenal cortex
The outer portion of the adrenal gland.
Corticosteroids
Steroid hormones released by the adrenal cortex in response to stress.
Glucocorticoids
Corticosteroids that influence glucose metabolism and the immune system (e.g., cortisol).
Mineralocorticoids
Corticosteroids that affect salt and water balance (e.g., aldosterone).
Catecholamines
Compounds secreted by the adrenal medulla in response to stress (e.g., epinephrine and norepinephrine).
Gonads
The testes and ovaries, which produce sex hormones.
Androgens
Male sex hormones, mainly testosterone.
Estrogens
Female sex hormones, most importantly estradiol.
Progesterone
A female sex hormone primarily involved in preparing and maintaining the uterus.
Pineal gland
A gland in the brain that secretes melatonin.
Melatonin
A hormone that helps regulate sleep-wake cycles (biorhythms).
Sexual dimorphism
The condition where males and females of the same species exhibit different physical or behavioral characteristics.
Homeostasis
The maintenance of a stable internal environment.
Synaptic signaling
Signaling that occurs when neurons secrete neurotransmitters that diffuse short distances and bind to receptors on target cells.
Hormone solubility
The ability of a hormone to dissolve in water or lipids, affecting its transport and receptor location.
Epinephrine
A hormone that mediates the body's response to short-term stress.
Releasing and inhibiting hormones
Hormones from the hypothalamus that control hormone production in the anterior pituitary.
Thyroid gland
An endocrine gland located in the neck that secretes thyroid hormones.
Gonadal sex hormones
Hormones produced by the testes and ovaries: androgens, estrogens, and progesterone.
Long-term regulation
Regulation that is long-lasting and pathway is the bloodstream.
Rapid response
Response that is very fast and pathway is the neurons.
Local regulators
Molecules that act over short distances, reaching target cells solely by diffusion.
Distant Target
It is the target of Neuroendocrine Signaling.
Nearby Target
It is the target of Synaptic Signaling.
Exocrine Glands
Secrete substances onto body surfaces or into body cavities.
Endocrine Glands
Secrete hormones into the bloodstream or surrounding fluid.
Hyper secretion
The action of excessive hormone secretion.
Hypo secretion
The action of insufficient hormone secretion.
Hormone cascade pathway
A hormone can stimulate the release of a series of other hormones, the last of which activates a non-endocrine target cell
Non-endocrine targets
Targets of Hypothalamic hormones.
Endocrine targets
Targets of Anterior pituitary hormones.
Goiter
Enlarged Thyroid Gland.
Sex hormones
Regulate formation of internal reproductive structures in human development
Mammory glands
Target of Oxytocin Hormone.
Kidney tubules
Target of ADH Hormone
Short-term
Effect Duration of Adrenal Medulla stress response.
Long-term
Effect Duration of Adrenal Cortex stress response.
Kidney
Organ Adjacent to the Adrenal Glands.
Bloodstream
Pathway of endocrine system.
Tropic Hormone
Hormone, which Trigger the Adrenal cortex.
Testosterone
Hormone, which stimulate development and maintenance of the male reproductive system
Estradiol
Hormone, which is responsible for maintenance of the female reproductive system and the development of female secondary sex characteristics
Pituitary stalk
A tubular connection to the pituitary gland.
Neurosecretory cell
A special kind of nerve cell that releases hormones instead of neurotransmitters.