replication
The copying of DNA
semiconservative
each double helix has one old and one new strand of nucleotides
during the s phase of interphase
when does replication occur
so after cell division each new cell has a copy of the DNA
why replicate dna
one point; 2
replication begins at ______ in prokaryotes and proceeds in __ directions
hundreds of points; 2
in eukaryotes replication occurs at ______ and proceeds in __ directions
replication fork
site of separation and replication
unwind and unzip the double helix
1st step of dna replication
add new nucleotides
second step of dna replication
bond together to super phosphate backbone
third step of dna replication
helicase
the enzyme that unwinds and unzips the dna strands at the replication fork exposing the nitrogenous bases
dna polymerase
enzyme that binds free nucleotides floating in the nucleus with the newly exposed nitrogen bases
5 to 3
dna builds from the __________ direction
3 to 5
dna is read _________
okazaki fragments
the fragments in dna segments that are produced by discontinuous synthesis
ligase
enzyme that binds nucleotides together forming new strands of dna (super glue)
chromatin
a combination of dna and proteins is called
codes for genetic information
function of nucleic acids
yes
are nucleic acids organic
genes
dna is made of ______ (small section of dna)
genome
all genetic info (DNA) in organism
chromosomes, chromatic, dna, genes, proteins, traits
copy/say this: chromosomes, chromatic, dna, genes, proteins, traits
nucleotides
the monomer of nucleic acids
sugar, phosphate, nitrogen base
three ingredients to a nucleotide
deoxyribosenucleic acid
dna stands for….
deoxyribose
what sugar is in dna?
adenine; guanine; cytosine; thymine
the four bases types of nitrogen bases in DNA
double helix
shape of dna
phosphates and sugars
back bone of dna
nitrogen bases
rungs of dna
h-bonds
what type of bond holds the nitrogen bases together in the center (the two strands of dna)
covalent
in dna sugars and phosphates are joined by ______ bonds
anti-parallel
dna is a____-p______; the two sides never cross or touch
3 prime
the side of dna that ends with no phosphate
5 prime
the side of dna that ends with a phosphate
3 prime to 5 prime
dna is read from ______ to _____
chargaff’s rule
the rule that states dna has an equal ration of A’s to T’s and C’s to G’s and that a goes with t and g goes with c
thymine
adenine pairs with
cytosine
guanine pairs with
ribonucleic acids
what is rna (what do the letters mean)
ribose
what sugar is in rna
adenine; guanine; cytosine; uracil
nitrogen bases of rna
single helix
shape of rna
messenger rna
the rna that brings instruction from the dna in the nucleus to the ribosomes in the cytoplasm
ribosomal rna
the rna that binds to the rna and uses the instructions to assemble the amino acids in the correct order to make the right protein (site of protein synthesis)
transfer rna
the rna that delivers amino acids to the ribisome to be assembled into proteins
single stranded
shape of mrna
single stranded loop of rna (upside down T)
shape of t rna
changes so it is clearly rna and no confusion
why is there uracil in rna and not dna
transcription
copying part of a DNA base sequence (gene) into an mRNA nucleotide sequence
interphase
when does rna happen
in the nucleus of the cell
where does transcription take place
so the genetic info can leave the nucleus and go to the ribisome
why does transcription happen
enzyme helicase binds to dna and zips apart the dna
using one dna strand as a template enzymes copy the dna base sequence
at the end of the gene transcription stops and the mrna molecules is released
DNA strand rewinds into double helix
steps of transcription
translation
the process of changing mRNA sequence into Amino Acid chains and linking together amino acids to make proteins
amino acids
monomers of proteins
ribosomes
where does protein synthesis/translation occur at
codon
3 bases in mRNA
the p site
where the tRNA first comes in contact with the mRNA complemant
the a site
where the amino acid from a tRNA is attached to another amino acid in a growing chain protein
the e site
the exit site where tRNA who have given up their amino acids to the protein leave the ribosomes
aug
what is the starting codon
una
uag
uga
what is the stop codon