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functions of bone
structure/support
protection of vital organs
serves as levers for movement
mineral storage
hemopoeisis
yellow marrow
structure/support function
serves as framework for the body and supports a lot of weight
protection of vital organs
cage
serve as levers for movement
gives a way for muscles to attach
mineral storage
calcium and phosphorous - if we get a signal for more calcium, osteoclasts break down bone
hemopoesis
bone makes blood, so forms blood cells (RBCs/WBCs/platelets)
yellow marrow
serves as a storage point for marrow, stores fat and there are stem cells there too
vascularity of bone
very vascular, heal well because there’s a good blood supply
parts of long bones
diaphysis, epiphysis, metaphysis, articular cartilage, periosteum, endosteum
diaphysis
shaft
epiphysis
ends
metaphysis
area between diaphysis and epiphysis, where growth plates are located
epiphyseal line
growth plate ossification; like a scar
articular cartilage
ends of bone where joints are located, made of hyaline cartilage and provides lubrication
periosteum
around the bone, fibrous membrane that surrounds the bone, there are two layers with protection and have blood vessels
2 layers of periosteum
dense CT - outside layer
mesenchymal (stem) cells
endosteum
lines the medullary cavity; also contains stem cells, houses yellow marrow
medullary cavity
hollow cavity within the diaphysis
bone is…
connective tissue, made of cells and IC substance
IC substance of bone
concrete, has collagen and elastic fibers/calcium salts to make it hard, secreted by osteoblasts, help make strong in tension/compression forces e
exterior bone
compact bone
interior bone
spongy bone/cancellous bone
bone cells
osteoprogenitor, osteoblast, osteoclast, osteocytes
osteoprogenitor
mesenchymal stem cells, can become anything, generates new cells associated with bone
osteoblasts
form bone, make IC substance
osteocytes
mature osteoblasts, responsible for maintaining cellular environment, sends signals to clasts and blasts to build/break down bone, secretes enzymes, surround themselves with lacunae
osteoclasts
bone eaters/reabsorption of bone, multinucleated cells, ruffled border
osteon/haversian system
functional unit of compact bone (what compact bone is made of), extends lengthwise through the bone
four major structures associated with an osteon
haversian canal, lamellae, lacunae, canaliculi
haversian canal
central canal, blood vessel/vein goes through center
lamellae
calcified matrix around central canal
canaliculi
little canals that radiate out to each lamellae to deliver nutrients to lamellae
lacunae
located between the lamellae in concentric arrangement, house the osteoblasts
volkmann’s canals
perforating canals, penetrate bone perpendicularly (horizontally) and bring blood vessels from the surface, interconnect osteon
spongy/cancellous/trabecular bone
deep to compact bone, contains no true osteons, consists of needle-like bony spikes called trabeculae
where is compact bone found
at the ends of long bone/flat bonew
what is compact bone missing
lamellae'/osteons
what does compact bone have still?
lacunae and canaliculiw
where does the blood supply come from
red marrow; surrounds and makes blood
red marrow
performs homopoeisis
types of bone
long bone, short bones, flat bones, irregular bones, floating bones, sutural bones
long bones
levers of system (even the metacarpals and hand bones are considered long bones)
short bones
cuboidal, found in places where we have limited range of motion, ex: carpals/tarsals
flat bones
2 thin layers of compact bone separated by spongy bone (ribs/scapula)
irregular bones
funny/peculiar shape, ex: sphenoid/ethmoid, vertebrae
floating bone/sesamoid bone
looks like a sesame seed, ex the patella and pisaform, float and aren’t really attached to much
sutural/wormian bones
only found in the skull, places where the sutures have an “extra suture”