ch. 57 rugs affecting gI secretions

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16 Terms

1
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gastric ulcer

symptoms worse after eating

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dudoneal ulcer

symptoms worse when stomach is empty

3
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cimetidine, Tagamet

histamine 2 receptor antagonist (H2RA)

  • Block release of hydrochloric acid in response to gastrin preventing acid release from parietal cells

  • tx of ulcers

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don’t take other antacids within 1 hour of taking this and give with/before meals and at bedtime

cimetidine

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antacids

chemical compounds that buffer or neutralize hydrochloric acid in the stomach and thereby increase the gastric pH

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sodium bicarbonate…nursing considerations

antacid

Take 1 and 3 hours after meals and at bedtime, take antacids at least 2 hours before taking other medications, take with full glass of water, shake bottle if liquid separation

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adverse effect of sodium bicarb

acid rebound..body produces more acid

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pantoprazole, Protonix

proton pump inhibitors (PPI)

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pantroprazole does what? nursing considerations?

preventative, suppress gastric acid secretions

  • take 30 minutes prior to eating, do not crush or chew, may be taken with antacids

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pantroprazole adverse effects

nausea, diarrhea, headache, high dose or long-term use carry a possible increased risk of bone fractures

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gastrointestinal protectants drug

sucralfate, Carafate “LOATS”

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sucralfate, Carafate

forms an ulcer-adherent complex at duodenal ulcer sites

  • basically puts a covering on the ulcers

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sucralfate, Carafate nursing considerations

avoid with renal failure or dialysis,

  • take on empty stomach 1 hour before or 2 hours after meals, give other drugs 30 minutes before or after

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adverse effects sucralfate, Carafate

constipation, dry mouth, metallic taste…risk of aluminum build up

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pancrelipase, Creon

digestive enzyme typically found in a healthy individual that aids in digestion and absorption of fats, proteins, and carbohydrates

  • aids in proper digestions

  • indication: pts deficient in this enzyme

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what are the 4 meds for tx of H. pylori

  • 2 antibiotics

  • 1 proton pump inhibitor (PPI)

  • bismuth salicylate (pepto bismol)