Cryptosporidium Opportunistic Intestinal Apicomplexa
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13 Terms
Which are the 2 Cryptosporidium spp?
Cryptosporidium hominis
Cryptosporidium parvum
Which disease is affected by Cryptosporidium spp? the most?
AIDS - causes GI infection
What is the transmission method for Cryptosporidium parvum and Cryptosporidium hominis?
Fecal -oral of OOCYST USUALLY IN WATER
What is the method of infection for Cryptosporidium spp.?
Oocyst → Sporozoite → Trophozoite → development meronts w/ merozoites → Micro/macrogamete → back to oocyt
What clinical infection does Cryptosporidium spp. cause?
Cryptosporidiosis
What symptoms are shown for Cryptosporidiosis in IMMUNOCOMPETENT patients?
WATERY DIARRHEA
Nausea
Vomiting
How does Cryptosporidium spp. Affect IMMUNOCOMPROMISED patients?
They are OPPORTUNISTIC so they affect immunocompromised people more.
POTENTIALLY LETHAL
REMEMBER AIDS
What chronic conditions can Cryptosporidium spp. cause?
Atrophy of INTESTINAL VILLI
Alter intestinal permeability
What is the diagnostic stage for Cryptosporidium hominis and Cryptosporidium parvum?
OOCYST
Which specimen is used to diagnose Cryptosporidium spp.?
Stool specimen
Which methods are used to identify Cryptosporidium spp. oocysts?
MODIFIED ACID-FAST
Fluorescent antibody stain
How does the Oocyst of Cryptosporidium spp. appear in the modified acid-fast test?
Bright red against a blue background
What are the characteristics of the Cryptosporidium oocyst?
4-6um
thick DOUBLE LAYER wall
centrally located granules
