Antigen Receptors/MHC
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14 Terms
1
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What causes the Ig domain to be stable?
Disulfide bonds
2
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Which antibodies do not have a hinge region?
IgE and IgM
3
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Which CDR uses VDJ recombination?
CDR3
4
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Which MHC has a larger groove without walls?
MHC II
5
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How many MHC molecules can be expressed through genes?
18
6
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What is the function of ERAP?
Chops up peptides to make them shorter
7
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Which MHC has peptides that may bulge outward?
MHC I
8
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Which MHC has peptides that are typically flatter?
MHC II
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Which genes are the most polymorphic?
MHC genes
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What transports peptide fragments from the cytosol to the ER?
TAP
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What is cross presentation?
Presentation of exogenously derived antigen peptides on MHC I
12
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What does CD1 present?
Lipid antigens
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What does MR1 present?
Metabolic derivatives to MIATs
14
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What is the function of HLA-E?
Inhibits NK cell activation
Note 
Flashcards (22)